ArticleBreast cancer research and treatment2021
International variation in breast cancer incidence and mortality in young women.
Article in Breast cancer research and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 2 of them syntheses that pooled it.
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Who cites it
66 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and meta-analysis of pregnancy-associated breast cancer incidence rate.BMC cancer · 2025Pooled it
- Factors influencing breast cancer screening practices among women worldwide: a systematic review of observational and qualitative studies.BMC women's health · 2024Pooled it
- Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer.The New England journal of medicine · 2023Trial
- Breast cancer mortality in Argentina, 1991-2023: a nationwide ecological study of spatiotemporal patterns and regional inequalities.Lancet regional health. Americas · 2026Article
- Development and validation of a nomogram to assess recurrence risk in young patients with breast cancer based on preoperative serum tumor markers.Gland surgery · 2026Article
- Review
- Factors associated with caregiving burden among spouses of patients with breast cancer: a cross-sectional study.BMC primary care · 2026Article
- The evidence for the use of peripheral blood indices in the diagnosis of breast cancer.The Journal of international medical research · 2026Review
- Incidence, mortality, and cumulative risk of cancer in adolescents and young adults in Switzerland.European journal of epidemiology · 2026Article
- An international cohort study of breast cancer survival in young women.BJC reports · 2026Article
- Increased risk of fracture among breast cancer patients: a nationwide retrospective cohort study.Journal of cancer survivorship : research and practice · 2026Article
- Molecular Dynamics and Energetic Insights into Novel PARP15 Inhibitors: A Structural Approach for Targeting BRCA-Mutated Breast Cancer.Current pharmaceutical design · 2026Article
- Prospective patient navigation program for young women with breast cancer: assessment and referrals to address medical and supportive care needs.The oncologist · 2025Article
- SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early-Onset of Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Phytosphingosine, a sphingolipid isolated from fungal endophyte Penicillium oxalicum, exerts cytotoxic effects against breast cancer cells and shows blood compatibility.Scientific reports · 2025Article
- Nomogram for development and validation of a prognosis prediction model for cancer-specific survival in young breast cancer patients with stage I-III based on the Surveillance, Epidemiology, and End Results (SEER) database.Translational cancer research · 2025Article
- Natural Compounds as Modulators of Ferroptosis: Mechanistic Insights and Therapeutic Prospects in Breast Cancer.Biomolecules · 2025Review
- Breast Cancer Awareness and Knowledge Among Women at a Municipal Hospital in Ghana: A Cross-Sectional Study.Cancer reports (Hoboken, N.J.) · 2025Article
- Addressing the Needs of Breast Cancer Survivors.Current oncology reports · 2025Review
- Stage at diagnosis and tumor characteristics among young women and men with breast cancer, in Ethiopia and Sweden, a descriptive cross-sectional study.BMC cancer · 2025Article
6 more citing papers are in PubMed but not listed here.
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Authors and funding
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Funding
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Abstract
purposeBreast cancer in young women (< 40 years) is rare and carries a poor prognosis relative to breast cancer in older women. Most studies examining global breast cancer patterns do not describe the trends in young women specifically.
methodsData from GLOBOCAN 2018 were used to compare breast cancer incidence and mortality rates among younger (ages 0-39) vs. older (ages 40+) women across 185 countries. The coefficient of variation (the ratio of the standard deviation to the mean) was used to quantify relative variability.
resultsThe risk of developing breast cancer to age 39 ranged from 0.13% in Guinea to 0.95% in South Korea (coefficient of variation: 46%), and the risk of death from breast cancer to age 39 ranged from 0.02% in China to 0.72% in Cameroon (coefficient of variation: 81%). In contrast, the risk of developing breast cancer to age 74 ranged from 1.5% in Mozambique to 12.2% in Belgium (coefficient of variation: 50%), and the risk of death from breast cancer to age 74 ranged from 0.65% in South Korea to 3.0% in Somalia (coefficient of variation: 36%).
conclusionsAmong young women, breast cancer mortality rates varied more worldwide than breast cancer incidence. In contrast, among older women/women of all ages, breast cancer incidence varied more than breast cancer mortality. Further research is required to examine the impact of stage at diagnosis, clinicopathologic features, and treatments received, on variations in the survival and mortality of breast cancer in young women around the world.
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