Evidence map›Paper›PMID 33145594›Full record

ArticleAmerican journal of epidemiology2021

How Long-Term Acute Care Hospitals Can Play an Important Role in Controlling Carbapenem-Resistant Enterobacteriaceae in a Region: A Simulation Modeling Study.

Bruce Y Lee, Sarah M Bartsch, Michael Y Lin, Lindsey Asti, Joel Welling, Leslie E Mueller, Jim Leonard, Shawn T Brown, Kruti Doshi, Sarah K Kemble and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Worsening Spread ofAnnals of internal medicine · 2023
    Article
  6. Regional Spread of blaNDM-1-Containing Klebsiella pneumoniae ST147 in Post-Acute Care Facilities.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Bruce Y Lee
Sarah M Bartsch
Michael Y Lin
Lindsey Asti
Joel Welling
Leslie E Mueller
Jim Leonard
Shawn T Brown
Kruti Doshi
Sarah K Kemble
Elizabeth A Mitgang
Robert A Weinstein
William E Trick
Mary K Hayden
The Graduate Center, CUNY · US

Funding

MULTILEVEL SYSTEMS-ORIENTED CHILDHOOD OBESITY STUDY IN CHINAU54HD070725 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CURRIERO, FRANK · 2011 to 2016
$15.9M
Virtual Population Obesity Prevention (VPOP) Labs: Computational, Multi-Scale Models for Obesity SolutionsU01HD086861 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2015 to 2019
$2.8M
Regional Healthcare Ecosystem Analyst for Healthcare Associated InfectionsR01HS023317 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2014 to 2014
$2.4M
Regional Healthcare Ecosystem Analyst (RHEA) Modeling the Environment (MODE): SARS-CoV-2R01GM127512 · NIGMS · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI LEE, BRUCE Y · 2020 to 2023
$2.1M
ACL HHS U54CK000481AHRQ HHS R01 HS023317NCEZID CDC HHS U54 CK000481NCEZID CDC HHS U54 CK000607NICHD NIH HHS U01 HD086861NICHD NIH HHS U54 HD070725NIGMS NIH HHS R01 GM127512
6 · The paper itself

Abstract

Typically, long-term acute care hospitals (LTACHs) have less experience in and incentives to implementing aggressive infection control for drug-resistant organisms such as carbapenem-resistant Enterobacteriaceae (CRE) than acute care hospitals. Decision makers need to understand how implementing control measures in LTACHs can impact CRE spread regionwide. Using our Chicago metropolitan region agent-based model to simulate CRE spread and control, we estimated that a prevention bundle in only LTACHs decreased prevalence by a relative 4.6%-17.1%, averted 1,090-2,795 new carriers, 273-722 infections and 37-87 deaths over 3 years and saved $30.5-$69.1 million, compared with no CRE control measures. When LTACHs and intensive care units intervened, prevalence decreased by a relative 21.2%. Adding LTACHs averted an additional 1,995 carriers, 513 infections, and 62 deaths, and saved $47.6 million beyond implementation in intensive care units alone. Thus, LTACHs may be more important than other acute care settings for controlling CRE, and regional efforts to control drug-resistant organisms should start with LTACHs as a centerpiece.

Indexed as

Carbapenem-Resistant EnterobacteriaceaeHospital AdministrationClinical ProtocolsComputer SimulationEnterobacteriaceae InfectionsHumansInfection ControlModels, TheoreticalCarbapenem-resistant Enterobacteriaceaehospitalslong-term acute care hospitalsprevention and control

Identifiers

PMID33145594
PMCPMC7936017
OpenAlexW3097403346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.