Evidence map›Paper›PMID 33145493›Full record

ArticleResearch (Washington, D.C.)2020

Single-Atom Nanozymes Linked Immunosorbent Assay for Sensitive Detection of A

Zhaoyuan Lyu, Shichao Ding, Nan Zhang, Yang Zhou, Nan Cheng, Maoyu Wang, Mingjie Xu, Zhenxing Feng, Xiangheng Niu, Yuan Cheng and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Research (Washington, D.C.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  3. Article
  4. Nanozymes Integrated Biochips Toward Smart Detection System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  5. Article
  6. Review
  7. Biomedical Applications of Nanozymes: An Enzymology Perspective.Angewandte Chemie (International ed. in English) · 2025
    Review
  8. [Advances in Nanozyme-Aptamer Systems for the Detection of Foodborne Pathogens].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Nanozyme-Based Strategies against Bone Infection.Research (Washington, D.C.) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Sensitive Immunochromatographic Determination ofNanomaterials (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhaoyuan LyuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.
Shichao DingSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.ORCID https://orcid.org/0000-0003-3795-306X
Nan ZhangInstitute of High Performance Computing, Institute of High Performance Computing, Singapore 138632.
Yang ZhouSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.
Nan ChengSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.
Maoyu WangSchool of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA.
Mingjie XuIrvine Materials Research Institute (IMRI), University of California, Irvine, CA 92697, USA.
Zhenxing FengSchool of Chemical, Biological, and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA.ORCID https://orcid.org/0000-0001-7598-5076
Xiangheng NiuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.
Yuan ChengInstitute of High Performance Computing, Institute of High Performance Computing, Singapore 138632.ORCID https://orcid.org/0000-0003-0061-3934
Chao ZhangDepartment of Electrical and Computer Engineering, National University of Singapore, Engineering Drive 3, Singapore 117583.
Dan DuSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.ORCID https://orcid.org/0000-0003-1952-4042
Yuehe LinSchool of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164, USA.ORCID https://orcid.org/0000-0003-3791-7587

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single-atom nanozymes (SANs) possess unique features of maximum atomic utilization and present highly assembled enzyme-like structure and remarkable enzyme-like activity. By introducing SANs into immunoassay, limitations of ELISA such as low stability of horseradish peroxidase (HRP) can be well addressed, thereby improving the performance of the immunoassays. In this work, we have developed novel Fe-N-C single-atom nanozymes (Fe-N

Identifiers

PMID33145493
PMCPMC7592081

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.