Evidence map›Paper›PMID 33145420›Full record

ArticleACS central science2020

Role of a Tyrosine Radical in Human Ceruloplasmin Catalysis.

Shiliang Tian, Stephen M Jones, Edward I Solomon

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Magnetic interactions between metal sites in complex enzymes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2025
    Review
  4. Review
  5. Does Tyrosine ProtectThe journal of physical chemistry. B · 2022
    Article
  6. Article
  7. Review
  8. Review
  9. The Resting Oxidized State of Small Laccase Analyzed with Paramagnetic NMR Spectroscopy.Chemphyschem : a European journal of chemical physics and physical chemistry · 2021
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shiliang TianDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.
Stephen M JonesDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.
Edward I SolomonDepartment of Chemistry, Stanford University, Stanford, California 94305, United States.
Stanford University · US

Funding

Structure/Function Correlations Over Copper EnzymesR01DK031450 · NIDDK · STANFORD UNIVERSITY · PI EDWARD I SOLOMON · 1986 to 2026
$8.7M
Understanding the reactivity of the most complex multicopper oxidase ceruloplasmin: insight into the reaction intermediates, mechanism and the roles of the additional type 1 copper sitesF32GM122174 · NIGMS · STANFORD UNIVERSITY · PI TIAN, SHILIANG · 2017 to 2019
$176k
NIDDK NIH HHS R01 DK031450NIGMS NIH HHS F32 GM122174
6 · The paper itself

Abstract

Multicopper oxidases (MCOs) are a large family of diverse enzymes found in both eukaryotes and prokaryotes that couple one-electron oxidations of various substrates to the four-electron reduction of O

Identifiers

PMID33145420
PMCPMC7596862
OpenAlexW3081955163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.