ArticleAsian journal of neurosurgery
Surgery in High-Grade Insular Tumors: Oncological and Seizure Outcomes from 41 Consecutive Patients.
Article in Asian journal of neurosurgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Transcortical versus transsylvian approaches for adult insular glioma resection: a systematic review with subanalysis by Berger-Sanai segmentation.Neurosurgical review · 2026Pooled it
- Seizure outcome after resection of insular glioma: a systematic review, meta-analysis, and institutional experience.Journal of neurosurgery · 2023Pooled it
- Transcortical versus Transsylvian Approach for Insular Gliomas: A Systematic Review and Meta-Analysis.Asian journal of neurosurgery · 2026Review
- Safety and Efficacy in the Transcortical and Transsylvian Approach in Insular High-Grade Gliomas: A Comparative Series of 58 Patients.Current oncology (Toronto, Ont.) · 2025Article
- Surgical treatment for insular gliomas. A systematic review and meta-analysis on behalf of the EANS neuro-oncology section.Brain & spine · 2024Review
- The Dilemma of Multifocality in Insular Tumors: Multicentricity versus Metastasis.Asian journal of neurosurgeryArticle
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInsular high-grade gliomas are uncommon and constitute approximately 10% of all intracranial high-grade gliomas. Several publications in the recent years have thrown substantial light in the understanding of insular low-grade gliomas. However, there is a paucity of information concerning the spectrum of high-grade lesions affecting the insula, the mode of presentation vis-à-vis low-grade gliomas, and the survival rates to modern therapy. AIMS AND
objectivesWe aim to highlight various clinical patterns, histo-pathological spectrum and the survival rates in patients with high-grade insular lesions. Also, we explore the factors that govern favourable outcomes. MATERIALS AND
methodsA retrospective study of 41 patients operated for high-grade insular tumors at our institute between March 2010 to December 2018 was done to evaluate the clinico-radiological features, surgical nuances, survival rates and seizure outcomes.
resultsRaised intracranial pressure was the most frequent clinical presentation (
conclusionInsular high-grade gliomas are commoner than thought and nearly half of these are grade IV tumors (51%). A presentation with seizures may indicate precursor low-grade gliomas and portend a better survival. A maximum "safe" surgical resection, keeping the postoperative quality of life in mind, should be the goal.
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Registered trials
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