Evidence map›Paper›PMID 33144873›Full record

ArticleComputational and mathematical methods in medicine2020

Evaluation of Multimodal Algorithms for the Segmentation of Multiparametric MRI Prostate Images.

Ying-Hwey Nai, Bernice W Teo, Nadya L Tan, Koby Yi Wei Chua, Chun Kit Wong, Sophie O'Doherty, Mary C Stephenson, Josh Schaefferkoetter, Yee Liang Thian, Edmund Chiong and 1 more

Abstract readEvaluation Study
In one paragraph

Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ying-Hwey NaiClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID https://orcid.org/0000-0002-6634-8785
Bernice W TeoNanyang Junior College, Singapore.
Nadya L TanSt. Joseph's Institution International, Singapore.
Koby Yi Wei ChuaAnglo-Chinese Independent, Singapore.
Chun Kit WongClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Sophie O'DohertyClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Mary C StephensonClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Josh SchaefferkoetterClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Yee Liang ThianDepartment of Diagnostic Imaging, National University Hospital, Singapore.
Edmund ChiongDepartment of Surgery (Urology), Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Anthonin ReilhacClinical Imaging Research Centre, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.ORCID https://orcid.org/0000-0002-9997-9540

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate segmentation in multiparametric magnetic resonance imaging (mpMRI) can help to support prostate cancer diagnosis and therapy treatment. However, manual segmentation of the prostate is subjective and time-consuming. Many deep learning monomodal networks have been developed for automatic whole prostate segmentation from T2-weighted MR images. We aimed to investigate the added value of multimodal networks in segmenting the prostate into the peripheral zone (PZ) and central gland (CG). We optimized and evaluated monomodal DenseVNet, multimodal ScaleNet, and monomodal and multimodal HighRes3DNet, which yielded dice score coefficients (DSC) of 0.875, 0.848, 0.858, and 0.890 in WG, respectively. Multimodal HighRes3DNet and ScaleNet yielded higher DSC with statistical differences in PZ and CG only compared to monomodal DenseVNet, indicating that multimodal networks added value by generating better segmentation between PZ and CG regions but did not improve the WG segmentation. No significant difference was observed in the apex and base of WG segmentation between monomodal and multimodal networks, indicating that the segmentations at the apex and base were more affected by the general network architecture. The number of training data was also varied for DenseVNet and HighRes3DNet, from 20 to 120 in steps of 20. DenseVNet was able to yield DSC of higher than 0.65 even for special cases, such as TURP or abnormal prostate, whereas HighRes3DNet's performance fluctuated with no trend despite being the best network overall. Multimodal networks did not add value in segmenting special cases but generally reduced variations in segmentation compared to the same matched monomodal network.

Indexed as

AlgorithmsComputational BiologyDatabases, FactualDeep LearningHumansImage Interpretation, Computer-AssistedMachine LearningMaleMathematical ConceptsMultiparametric Magnetic Resonance ImagingNeural Networks, ComputerPattern Recognition, AutomatedProstatic Neoplasms

Identifiers

PMID33144873
PMCPMC7596462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.