Evidence map›Paper›PMID 33144872›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Kang-Xian Pills Inhibit Inflammatory Response and Decrease Gut Permeability to Treat Carbon Tetrachloride-Induced Chronic Hepatic Injury through Modulating Gut Microbiota.

Li Wang, Huantian Cui, Yuting Li, Min Cao, Shanshan Man, Liying Guo, Jing Miao, Jianwei Jia, Yuhong Bian, Zhaiyi Zhang

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Li WangTianjin Second People's Hospital, Tianjin, China.
Huantian CuiShandong Provincial Key Laboratory of Animal Cell and Developmental Biology, School of Life Sciences, Shandong University, Qingdao, China.
Yuting LiTianjin University of Traditional Chinese Medicine, Tianjin, China.
Min CaoTianjin University of Traditional Chinese Medicine, Tianjin, China.
Shanshan ManTianjin Second People's Hospital, Tianjin, China.
Liying GuoTianjin Second People's Hospital, Tianjin, China.
Jing MiaoTianjin Second People's Hospital, Tianjin, China.
Jianwei JiaTianjin Second People's Hospital, Tianjin, China.
Yuhong BianTianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID https://orcid.org/0000-0002-4802-1025
Zhaiyi ZhangTianjin University of Traditional Chinese Medicine, Tianjin, China.ORCID https://orcid.org/0000-0002-9471-4252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kang-Xian (KX) pills have been clinically used for the treatment of chronic hepatic injury (CHI). However, the mechanisms of KX on CHI remain unknown. The aim of this study mainly focused on the anti-inflammatory effects of KX in a CHI mouse model based on modulating gut microbiota and gut permeability. We first established a CHI model using carbon tetrachloride (CCl

Identifiers

PMID33144872
PMCPMC7596455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.