ArticleScientific reports2020
Concentration-driven phase transition and self-assembly in drying droplets of diluting whole blood.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A Comprehensive Numerical Model of Thrombus Embolization: Fluid-Thrombus Interactions Through a Coupled Computational Fluid Dynamics - Peridynamics Framework.Computer methods in applied mechanics and engineering · 2026Article
- Role of motility and nutrient availability in drying patterns of algal droplets.Scientific reports · 2024Article
- Deep learning applied to analyze patterns from evaporated droplets of Viscum album extracts.Scientific reports · 2022Article
- Evaporation Patterns of Dextran-Poly(Ethylene Glycol) Droplets with Changes in Wettability and Compatibility.Life (Basel, Switzerland) · 2022Article
- Texture Analysis of Dried Droplets for the Quality Control of Medicines.Sensors (Basel, Switzerland) · 2021Article
- Temperature and Concentration Dependence of Human Whole Blood and Protein Drying Droplets.Biomolecules · 2021Article
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Authors and funding
4 authors.
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Abstract
Multi-colloidal systems exhibit a variety of structural and functional complexity owing to their ability to interact amongst different components into self-assembled structures. This paper presents experimental confirmations that reveal an interesting sharp phase transition during the drying state and in the dried film as a function of diluting concentrations ranging from 100% (undiluted whole blood) to 12.5% (diluted concentrations). An additional complementary contact angle measurement exhibits a monotonic decrease with a peak as a function of drying. This peak is related to a change in visco-elasticity that decreases with dilution, and disappears at the dilution concentration for the observed phase transition equivalent to 62% (v/v). This unique behavior is clearly commensurate with the optical image statistics and morphological analysis; and it is driven by the decrease in the interactions between various components within this bio-colloid. The implications of these phenomenal systems may address many open-ended questions of complex hierarchical structures.
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