Evidence map›Paper›PMID 33144549›Full record

ArticleJournal of microbiology and biotechnology2021

In Vitro

Ji-Yeon Kang, Hong-Yeol Choi, Dong-Il Kim, Ohsuk Kwon, Doo-Byoung Oh

Open access · bronzeAbstract read
In one paragraph

Article in Journal of microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ji-Yeon KangKorea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Hong-Yeol ChoiDepartment of Biological Engineering, Inha University, Incheon 22212, Republic of Korea.
Dong-Il KimDepartment of Biological Engineering, Inha University, Incheon 22212, Republic of Korea.
Ohsuk KwonKorea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Doo-Byoung OhKorea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Republic of Korea.
Korea Research Institute of Bioscience and Biotechnology · KRInha University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzyme replacement therapy for lysosomal storage diseases usually requires recombinant enzymes containing mannose-6-phosphate (M6P) glycans for cellular uptake and lysosomal targeting. For the first time, a strategy is established here for the in vitro mannosyl-phosphorylation of high-mannose type

Indexed as

HumansHydrogen-Ion ConcentrationMannosephosphatesPhosphorylationPichiaPolysaccharidesRecombinant ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSaccharomycetalesTemperaturemannose-6-phosphateMannosephosphatesPolysaccharidesRecombinant ProteinsSaccharomyces cerevisiae Proteinsenzyme replacement therapylysosomal storage diseaseMannose-6-phosphateMannosyl-phosphorylationMnn14

Identifiers

PMID33144549
PMCPMC9705852
OpenAlexW3094810881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.