Evidence map›Paper›PMID 33144480›Full record

ReviewIn vivo (Athens, Greece)

Solitary Fibrous Tumor of the Orbit: A Clinicopathologic Study of Two Cases With Review of the Literature.

Mizuho Mitamura, Satoru Kase, Yasuo Suzuki, Takatoshi Sakaguchi, Yuka Suimon, Yoko Dong, Kanako C Hatanaka, Toshiya Sinohara, Manabu Kase, Susumu Ishida

Open access · diamondAbstract readCase ReportsReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mizuho MitamuraDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Satoru KaseDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan kaseron@med.hokudai.ac.jp.
Yasuo SuzukiDepartment of Ophthalmology, Orbital Disease & Neuro-Ophthalmology Center, Teine Keijinkai Hospital, Sapporo, Japan.
Takatoshi SakaguchiDepartment of Ophthalmology, Orbital Disease & Neuro-Ophthalmology Center, Teine Keijinkai Hospital, Sapporo, Japan.
Yuka SuimonDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Yoko DongDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Kanako C HatanakaDepartment of Surgical Pathology, Hokkaido University Hospital, Sapporo, Japan.
Toshiya SinoharaDepartment of Pathology, Teine Keijinkai Hospital, Sapporo, Japan.
Manabu KaseDepartment of Ophthalmology, Orbital Disease & Neuro-Ophthalmology Center, Teine Keijinkai Hospital, Sapporo, Japan.
Susumu IshidaDepartment of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Hokkaido University · JPTeine Keijinkai Hospital · JPHokkaido University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimOrbital solitary fibrous tumor (SFT) is a rare lesion among orbital tumors, which can be misdiagnosed as another mesenchymal tumor. In this study we report two cases of orbital SFT, focusing on the imaging and pathological findings of the vascular structure inside the tumor. CASE REPORT: A 26-year-old woman and 43-year-old man presented with orbital SFT. The pathological findings revealed a patternless growth pattern of the tumor cells and hemangiopericytoma-like vascularity as well as thickened, dilated blood vessels within the tumor tissue. Tumor cells revealed a diffuse strong positivity for cluster of differentiation 34 (CD34) and signal transducer and activator of transcription 6 (STAT6) in both cases, while B-cell lymphoma 2 (bcl-2) and CD99 were positive in one case. Characteristic findings within the tumor were the arterial components, where a variety of STAT6, CD99 and bcl-2-positive smooth muscle cells were intermingled.

conclusionHistologically, the tumor tissues might be characterized by not only conventional hemangiopericytoma-like vasculature but also dilated arterial vessels, which were shown to be part of the tumor components.

Indexed as

HemangiopericytomaOrbital NeoplasmsSolitary Fibrous TumorsAdultBiomarkers, TumorFemaleHumansMaleOrbitSTAT6 Transcription FactorBiomarkers, TumorSTAT6 Transcription Factorfeeding arteryMesenchymal tumororbital tumorsolitary fibrous tumor

Identifiers

PMID33144480
PMCPMC7811632
OpenAlexW3095152632

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.