Evidence map›Paper›PMID 33144470›Full record

ArticleIn vivo (Athens, Greece)

Clinicopathological Data and Treatment Modalities for Pancreatic Somatostatinomas.

Aikaterini Mastoraki, Dimitrios Schizas, Eleni Papoutsi, Vasiliki Ntella, Prodromos Kanavidis, Athanasios Sioulas, Marina Tsoli, Georgios Charalampopoulos, Michail Vailas, Evangelos Felekouras

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Aikaterini MastorakiFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece dr_kamast@yahoo.gr.
Dimitrios SchizasFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Eleni PapoutsiFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Vasiliki NtellaFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Prodromos KanavidisFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Athanasios SioulasDepartment of Gastroenterology, Hygeia Hospital, Athens, Greece.
Marina TsoliFirst Department of Internal Medicine, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Georgios CharalampopoulosDepartment of Radiology, Laikon General Hospital, Athens, Greece.
Michail VailasFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Evangelos FelekourasFirst Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Laiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GRHygeia Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimSomatostatinomas (SSomas) constitute a rare neuroendocrine tumor. The purpose of this study was to evaluate the current published literature about pancreatic SSomas and report epidemiologic and clinicopathologic data for this entity. PATIENTS AND

methodsA combined automated and manual systematic database search of the literature was performed using electronic search engines (Medline PubMed, Scopus, Ovid and Cochrane Library), until February 2020. Statistical analysis was performed using the R language and environment for statistical computing.

resultsOverall, the research revealed a total of 36 pancreatic SSoma cases. Patient mean age was 50.25 years. The most common pancreatic location was the pancreatic head (61.8%). The most frequent clinical symptom was abdominal pain (61.1%). Diagnostic algorithm most often included Computed Tomography and biopsy; surgical resection was performed in 28 cases. Out of the 36 cases, 22 had been diagnosed with a metastatic tumor and metastasectomy was performed in 6 patients with a worse overall survival (OS) (p=0.029). In total, OS was 47.74 months.

conclusionPatients with metastatic disease did not benefit from metastasectomy, but the sample size was small to reach definite conclusions. However, further studies with longer follow-up are needed for a better evaluation of these results.

Indexed as

MetastasectomyNeuroendocrine TumorsPancreatic NeoplasmsSomatostatinomaHumansMiddle AgedTomography, X-Ray Computeddiagnosisneuroendocrine tumorspancreasSomatostatinomatherapeutic strategies

Identifiers

PMID33144470
PMCPMC7811659
OpenAlexW3095221658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.