Evidence map›Paper›PMID 33144468›Full record

ArticleIn vivo (Athens, Greece)

Oncological Outcomes of Pathological T1 Lower Rectal Cancer Patients With or Without Preoperative Chemoradiotherapy.

Tetsuro Taira, Hiroaki Nozawa, Kazushige Kawai, Kazuhito Sasaki, Koji Murono, Manabu Kaneko, Shigenobu Emoto, Yuuki Iida, Hiroaki Ishii, Yuichiro Yokoyama and 3 more

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Tetsuro TairaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan ttaira.tky@gmail.com.
Hiroaki NozawaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Kazushige KawaiDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Kazuhito SasakiDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Koji MuronoDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Manabu KanekoDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Shigenobu EmotoDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Yuuki IidaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Hiroaki IshiiDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Yuichiro YokoyamaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Hiroyuki AnzaiDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Hirofumi SonodaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Soichiro IshiharaDepartment of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
The University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimIt remains unclear whether rectal cancers down-staged by preoperative chemoradiotherapy (CRT) have similar prognoses to those of the same stage without preoperative CRT. We compared prognoses of pT1 rectal cancer patients stratified by preoperative CRT. PATIENTS AND

methodsWe retrieved data of patients with pathological T1 rectal cancer between 2003 and 2020. Patients were divided into the "ypT1 group" who received preoperative CRT following surgery and the "pT1 group" who underwent surgery alone. Factors associated with relapse-free survival (RFS) were investigated.

resultsAmong 86 patients, ypT1 and pT1 groups comprised 18 and 68 patients, respectively. There was no significant difference in RFS between the groups (p=0.19). Tumor location within 5 cm from the anal verge was associated with recurrence (hazard ratio: 0.13, p=0.034).

conclusionThe prognosis of patients with ypT1 rectal cancer was similar to that of patients with pT1. Low tumor location was a poor prognostic factor.

Indexed as

Neoplasm Recurrence, LocalRectal NeoplasmsChemoradiotherapyHumansNeoplasm StagingPreoperative CarePrognosisRetrospective StudiesPreoperative chemoradiotherapyprognosisrectal cancer

Identifiers

PMID33144468
PMCPMC7811633
OpenAlexW3096931035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.