Evidence map›Paper›PMID 33144379›Full record

ArticlemBio2020

SPOR Proteins Are Required for Functionality of Class A Penicillin-Binding Proteins in Escherichia coli.

Manuel Pazos, Katharina Peters, Adrien Boes, Yalda Safaei, Calem Kenward, Nathanael A Caveney, Cedric Laguri, Eefjan Breukink, Natalie C J Strynadka, Jean-Pierre Simorre and 2 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Lytic transglycosylase Slt of Pseudomonas aeruginosa as a periplasmic hub protein.Protein science : a publication of the Protein Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 6 countries.

Manuel Pazos *Centre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom Manuel.Pazos@newcastle.ac.uk Waldemar.Vollmer@newcastle.ac.uk.
Katharina Peters *Centre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Adrien BoesInBioS-Centre d'Ingénierie des Protéines, Liège University, Liège, Belgium.
Yalda SafaeiBiochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, British Columbia, Canada.
Calem KenwardBiochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, British Columbia, Canada.
Nathanael A CaveneyDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-4828-3479
Cedric LaguriUniversity of Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Eefjan BreukinkMembrane Biochemistry and Biophysics, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands.
Natalie C J StrynadkaBiochemistry and Molecular Biology and Centre for Blood Research, The University of British Columbia, Vancouver, British Columbia, Canada.
Jean-Pierre SimorreUniversity of Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Mohammed TerrakInBioS-Centre d'Ingénierie des Protéines, Liège University, Liège, Belgium.
Waldemar VollmerCentre for Bacterial Cell Biology, Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom Manuel.Pazos@newcastle.ac.uk Waldemar.Vollmer@newcastle.ac.uk.ORCID 0000-0003-0408-8567
Newcastle University · GBUniversity of British Columbia · CACentre National de la Recherche Scientifique · FRUniversity of Liège · BEStanford University · USUtrecht University · NL

Funding

CIHRHoward Hughes Medical InstituteMedical Research Council MR/N002679/1Wellcome TrustWellcome Trust 101824/Z/13/Z
6 · The paper itself

Abstract

Sporulation-related repeat (SPOR) domains are present in many bacterial cell envelope proteins and are known to bind peptidoglycan.

Indexed as

Anti-Bacterial AgentsCefsulodinEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsModels, MolecularPenicillin-Binding ProteinsPeptidoglycanPeptidoglycan GlycosyltransferaseProtein BindingProtein ConformationAnti-Bacterial AgentsCefsulodinEscherichia coli ProteinsPenicillin-Binding ProteinsPeptidoglycanPeptidoglycan Glycosyltransferasecell divisionpeptidoglycanpeptidoglycan synthasesSPOR domain

Identifiers

PMID33144379
PMCPMC7642682
OpenAlexW3094997234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.