Evidence map›Paper›PMID 33144365›Full record

ArticleBJGP open2020

General practice recommendations for the topical treatment of psoriasis: a modified-Delphi approach.

Diamant Thaçi, Pablo de la Cueva, Andrew E Pink, Ahmad Jalili, Siegfried Segaert, Kasper F Hjuler, Piergiacomo Calzavara-Pinton

Open access · goldAbstract read
In one paragraph

Article in BJGP open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 7 countries.

Diamant ThaçiInstitute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany.
Pablo de la CuevaDepartment of Dermatology, University Hospital Infanta Leonor de Madrid, Madrid, Spain.ORCID https://orcid.org/0000-0003-4807-3551
Andrew E PinkSt John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Ahmad JaliliDepartment of Dermatology, Bürgenstock Medical Center, Obbürgen, Switzerland.
Siegfried SegaertConsultant Dermatologist, Bonheiden, Belgium.
Kasper F HjulerDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Piergiacomo Calzavara-PintonDepartment of Dermatology, University of Brescia, Brescia, Italy piergiacomo.calzavarapinton@unibs.it.
Aarhus University Hospital · DKBrescia University · USBritish Association of Dermatologists · GBGuy's and St Thomas' NHS Foundation Trust · GBHospital Universitario Infanta Leonor · ESUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough GPs are usually the first port of call for patients with psoriasis, there is a lack of consistent and up-to-date clinical recommendations for interventions for patients with mild-to-moderate disease.

aimTo provide practical recommendations for GPs to optimise psoriasis treatment with topical therapies in four key areas: patient identification; treatment decision making with topical theory; topical treatment outcomes; and optimising patient adherence. DESIGN &

settingA consensus-seeking programme (modified-Delphi approach) was undertaken to assess the literature and develop recommendations for GPs, based on evidence and expert opinion.

methodThree dermatologists compiled 47 questions that were subsequently ranked and refined according to clinical relevance or importance using an online survey. Thereafter, 19 dermatologists from different European countries developed statements and clinical recommendations for the top seven ranked topical treatment and GP-relevant questions based on literature research and clinical experience. The final recommendations were based on 100% agreement among a final panel of seven experts.

resultsThe clinical effectiveness, fast onset of action, tolerability, cosmetic acceptability, and practicability of topical therapy, in addition to good physician-patient communication, are important for optimising patient adherence and maximising efficacy. Topical treatments combining corticosteroids and vitamin D analogues (administered as fixed combination) are well-established first-line treatments in mild-to-moderate psoriasis.

conclusionSimple but detailed practical guidance is provided, which is formed from evidence and expert clinical recommendations, to assist GPs with the optimal use of topical agents based on efficacy, tolerability, disease severity, site of psoriasis, patient lifestyle and preferences, and intended duration of treatment.

Indexed as

adherencegeneral practitionersprimary health carepsoriasisrecommendationstopical treatment

Identifiers

PMID33144365
PMCPMC7880171
OpenAlexW3096018126

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.