Evidence map›Paper›PMID 33144357›Full record

ArticleJournal of clinical pathology2022

Extended storage of SARS-CoV-2 nasopharyngeal swabs does not negatively impact results of molecular-based testing across three clinical platforms.

Karin A Skalina, D Y Goldstein, Jaffar Sulail, Eunkyu Hahm, Momka Narlieva, Wendy Szymczak, Amy S Fox

Abstract read
In one paragraph

Article in Journal of clinical pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Stability of GenotubeViruses · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Ecoimmunology in the field: Measuring multiple dimensions of immune function with minimally invasive, field-adapted techniques.American journal of human biology : the official journal of the Human Biology Council · 2022
    Review
  7. A pandemic guided by the SARS-CoV-2 PCR test: What should the clinician know?South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2022
    Article
  8. Article
  9. Article
  10. Detection of SARS-CoV-2 variants by Abbott molecular, antigen, and serological tests.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022
    Article
  11. Article
  12. Survival and detection of SARS-CoV-2 variants on dry swabs post storage.Frontiers in cellular and infection microbiology · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karin A SkalinaPathology, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID http://orcid.org/0000-0002-2212-3533
D Y GoldsteinPathology, Montefiore Medical Center, Bronx, New York, USA dogoldst@montefiore.org.ORCID http://orcid.org/0000-0001-6367-8335
Jaffar SulailPathology, Montefiore Medical Center, Bronx, New York, USA.
Eunkyu HahmPathology, Montefiore Medical Center, Bronx, New York, USA.
Momka NarlievaPathology, Montefiore Medical Center, Bronx, New York, USA.
Wendy SzymczakPathology, Montefiore Medical Center, Bronx, New York, USA.
Amy S FoxPathology, Montefiore Medical Center, Bronx, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the global outbreak of COVID-19, the demand for testing rapidly increased and quickly exceeded the testing capacities of many laboratories. Clinical tests which receive CE (Conformité Européenne) and Food and Drug Administration (FDA) authorisations cannot always be tested thoroughly in a real-world environment. Here we demonstrate the long-term stability of nasopharyngeal swab specimens for SARS-CoV-2 molecular testing across three assays recently approved by the US FDA under Emergency Use Authorization. This study demonstrates that nasopharyngeal swab specimens can be stored under refrigeration or even ambient conditions for 21 days without clinically impacting the results of the real-time reverse transcriptase-PCR testing.

Indexed as

COVID-19COVID-19 Nucleic Acid TestingHumansLaboratories, HospitalNasopharynxRefrigerationSARS-CoV-2Specimen HandlingTime Factorshospitalmicrobiologypathology departmentpolymerase chain reactionvirology

Identifiers

PMID33144357
PMCPMC8685649

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.