Evidence map›Paper›PMID 33143686›Full record

ArticleBMC ophthalmology2020

Age distribution and associated factors of cornea biomechanical parameter stress-strain index in Chinese healthy population.

Guihua Liu, Hua Rong, Ruxia Pei, Bei Du, Nan Jin, Di Wang, Chengcheng Jin, Ruihua Wei

Abstract read
In one paragraph

Article in BMC ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  7. Corneal strain influences keratocyte proliferation and migration through upregulation of ALDH3A1 expression.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  8. Biomechanical properties measured with dynamic Scheimpflug analyzer in central serous chorioretinopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  9. Article
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  14. Effect of prostaglandin analogues on the biomechanical corneal properties in patients with open-angle glaucoma and ocular hypertension measured with dynamic scheimpflug analyzer.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Observational
  15. Article
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  19. The Effect of Axial Length Elongation on Corneal Biomechanical Property.Frontiers in bioengineering and biotechnology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Guihua LiuTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Hua RongTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Ruxia PeiTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Bei DuTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Nan JinTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Di WangTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Chengcheng JinTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China.
Ruihua WeiTianjin International Joint Research and Development Centre of Ophthalmology and Vision Science, Postal address: 251 Fukang Road, Nankai District, Tianjin, China. rwei@tmu.edu.cn.ORCID https://orcid.org/0000-0002-9708-0355

Funding

Natural Science Foundation of Tianjin City 81770901
6 · The paper itself

Abstract

backgroundTo investigate the new cornea biomechanical parameter stress-strain index (SSI) in Chinese healthy people and the factors associated with SSI.

methodsA total of 175 eyes from 175 participants were included in this study. Axial length was measured with the Lenstar LS-900. Pentacam measured curvature of the cornea and anterior chamber volume (ACV). Cornea biomechanical properties assessments were performed by corneal visualization Scheimpflug technology (Corvis ST). Student's t-test, one-way ANOVA, partial least square linear regression (PLSLR) and linear mixed effects (LME) model were used in the statistical analysis.

resultsThe mean (±SD) SSI was 1.14 ± 0.22 (range, 0.66-1.78) in all subjects and affected by age significantly after age of 35 (P < 0.05). In LME models, SSI was significantly associated with age (β = 0.526, P < 0.001), axial length (AL) (β = - 0.541, P < 0.001), intraocular pressure (IOP) (β = 0.326, P < 0.001) and steepest radius of anterior corneal curvature (RsF) (β = 0.229, P < 0.001) but not with ACV, biomechanical corrected intraocular pressure (bIOP), flattest radius of anterior corneal curvature (RfF) or central corneal thickness (CCT) (P > 0.05 for each).

conclusionsSSI increased with age after the age of 35. In addition to age, SSI was positively correlated with RsF and IOP, while negatively correlated with AL.

Indexed as

CorneaTonometry, OcularAge DistributionBiomechanical PhenomenaChinaHumansIntraocular PressureAnterior segment parametersChinese populationCorneal biomechanicsCorvis STStress-strain index

Identifiers

PMID33143686
PMCPMC7607623

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.