Evidence map›Paper›PMID 33143540›Full record

ReviewThe journal of vascular access2021

Hemodialysis vascular access affects heart function and outcomes: Tips for choosing the right access for the individual patient.

Jan Malik, Carlo Lomonte, Joris Rotmans, Eva Chytilova, Ramon Roca-Tey, Mariusz Kusztal, Tomas Grus, Maurizio Gallieni

Open access · hybridAbstract readReview
In one paragraph

Review in The journal of vascular access, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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  10. Reliability and benefit of estimated continuous cardiac output measurement using shunt-side SpOTherapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 5 countries.

Jan MalikThird Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-2386-3293
Carlo LomonteMiulli General Hospital, Division of Nephrology, Acquaviva delle Fonti, Italy.
Joris RotmansDepartment of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-9682-6234
Eva ChytilovaThird Department of Internal Medicine, General University Hospital, First Faculty of Medicine, Charles University, Prague, Czech Republic.ORCID https://orcid.org/0000-0002-9283-3661
Ramon Roca-TeyDepartment of Nephrology, Hospital de Mollet, Fundació Sanitària Mollet, Barcelona, Spain.
Mariusz KusztalDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, Wroclaw, Poland.ORCID https://orcid.org/0000-0002-6502-0374
Tomas GrusSecond Department of Surgery, General University Hospital, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Maurizio GallieniNephrology and Dialysis Unit - ASST Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences 'L. Sacco', University of Milano, Milano, Italy.ORCID https://orcid.org/0000-0002-2011-2160
Charles University · CZInstitut de Seguretat Pública de Catalunya · ESLeiden University Medical Center · NLOspedale Generale Regionale Francesco Miulli · ITUniversity of Milan · ITWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease is associated with increased cardiovascular morbidity and mortality. A well-functioning vascular access is associated with improved survival and among the available types of vascular access the arterio-venous (AV) fistula is the one associated with the best outcomes. However, AV access may affect heart function and, in some patients, could worsen the clinical status. This review article focuses on the specific cardiovascular hemodynamics of dialysis patients and how it is affected by the AV access; the effects of an excessive increase in AV access flow, leading to high-output heart failure; congestive heart failure in CKD patients and the contraindications to AV access; pulmonary hypertension. In severe heart failure, peritoneal dialysis (PD) might be the better choice for cardiac health, but if contraindicated suggestions for vascular access selection are provided based on the individual clinical presentation. Management of the AV access after kidney transplantation is also addressed, considering the cardiovascular benefit of AV access ligation compared to the advantage of having a functioning AVF as backup in case of allograft failure. In PD patients, who need to switch to hemodialysis, vascular access should be created timely. The influence of AV access in patients undergoing cardiac surgery for valvular or ischemic heart disease is also addressed. Cardiovascular implantable electronic devices are increasingly implanted in dialysis patients, but when doing so, the type and location of vascular access should be considered.

Indexed as

Arteriovenous FistulaArteriovenous Shunt, SurgicalKidney Failure, ChronicKidney TransplantationRenal Insufficiency, ChronicHumansLigationRenal Dialysisarteriovenous fistulaChronic kidney diseaseheart failurehemodialysisperitoneal dialysispulmonary hypertension

Identifiers

PMID33143540
PMCPMC8606800
OpenAlexW3094698114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.