Evidence map›Paper›PMID 33143501›Full record

ArticleActa orthopaedica2021

Association between fixation type and revision risk in total knee arthroplasty patients aged 65 years and older: a cohort study of 265,877 patients from the Nordic Arthroplasty Register Association 2000-2016.

Tero Irmola, Ville Ponkilainen, Keijo T Mäkelä, Otto Robertsson, Annette W-Dahl, Ove Furnes, Anne M Fenstad, Alma B Pedersen, Henrik M Schrøder, Antti Eskelinen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Acta orthopaedica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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  15. No effect of fixation type on early and late mortality after total knee arthroplasty: a Dutch arthroplasty register study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 4 countries.

Tero IrmolaCoxa Hospital for Joint Replacement, and Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland.
Ville PonkilainenCoxa Hospital for Joint Replacement, and Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland.
Keijo T MäkeläFinnish Arthroplasty Register, National Institute for Health and Welfare, Helsinki, Finland.
Otto RobertssonThe Swedish Knee Arthroplasty Register, Department of Orthopedics, Skane University Hospital, Lund, Sweden. Department of Clinical Sciences, Orthopedics, Lund University, Sweden.
Annette W-DahlThe Swedish Knee Arthroplasty Register, Department of Orthopedics, Skane University Hospital, Lund, Sweden. Department of Clinical Sciences, Orthopedics, Lund University, Sweden.
Ove FurnesThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.
Anne M FenstadThe Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway.
Alma B PedersenDepartment of Clinical Epidemiology, Aarhus University Hospital. Denmark and Danish Knee Arthroplasty Registry.
Henrik M SchrøderDepartment of Orthopaedic Surgery, Naestved Hospital, Denmark.
Antti EskelinenCoxa Hospital for Joint Replacement, and Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland.
Mika J NiemeläinenCoxa Hospital for Joint Replacement, and Faculty of Medicine and Health Technologies, University of Tampere, Tampere, Finland.
Coxa Hospital · FIHaukeland University Hospital · NOTampere University · FIAarhus University Hospital · DKLund University · SENæstved Sygehus · DKSkåne University Hospital · SETurku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose - The population of the Nordic countries is aging and the number of elderly patients undergoing total knee arthroplasty (TKA) is also expected to increase. Reliable fixation methods are essential to avoid revisions. We compared the survival of different TKA fixation concepts with cemented fixation as the gold standard.Patients and methods - We used data from the Nordic Arthroplasty Register Association (NARA) database of 265,877 unconstrained TKAs performed for patients aged ≥ 65 years with primary knee osteoarthritis between 2000 and 2016. Kaplan-Meier (KM) survival analysis with 95% confidence intervals (CI) and the Cox multiple-regression model were used to compare the revision risk of the fixation methods.Results - Cemented fixation was used in 243,166 cases, uncemented in 8,000, hybrid (uncemented femur with cemented tibia) in 14,248, and inverse hybrid (cemented femur with uncemented tibia) fixation in 463 cases. The 10-year KM survivorship (95% CI) of cemented TKAs was 96% (96 - 97), uncemented 94% (94 - 95), hybrid 96% (96 - 96), and inverse hybrid 96% (94 - 99), respectively. Uncemented TKA was associated with increased risk of revision compared with the cemented TKA; the adjusted hazard ratio was 1.3 (95% CI 1.1 - 1.4).Interpretation - Cemented, hybrid, and inverse hybrid TKAs showed 10-year survival rates exceeding 95%. Uncemented fixation was associated with an increased risk of revision in comparison with cemented fixation. As both hybrid and inverse hybrid fixation were used in only a limited number of TKAs, indicating possibility of selection bias in their favor, cemented TKA still remains the gold standard, as it works reliably in the hands of many.

Indexed as

CementationKnee ProsthesisProsthesis DesignAgedArthroplasty, Replacement, KneeCohort StudiesFemaleHumansMaleProsthesis FailureRegistriesReoperationScandinavian and Nordic Countries

Identifiers

PMID33143501
PMCPMC7919873
OpenAlexW3097700675

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.