Evidence map›Paper›PMID 33143371›Full record

ReviewInternational journal of molecular sciences2020

Cardiovascular Disease and SARS-CoV-2: the Role of Host Immune Response Versus Direct Viral Injury.

Federico Biscetti, Maria Margherita Rando, Elisabetta Nardella, Andrea Leonardo Cecchini, Piergiorgio Bruno, Raffaele Landolfi, Andrea Flex

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Cardiovascular Outcomes in the Acute Phase of COVID-19.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federico BiscettiFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.ORCID 0000-0001-7449-657X
Maria Margherita RandoInternal Medicine and Vascular Diseases Unit, 00168 Roma, Italy.
Elisabetta NardellaInternal Medicine and Vascular Diseases Unit, 00168 Roma, Italy.ORCID 0000-0001-7119-0364
Andrea Leonardo CecchiniInternal Medicine and Vascular Diseases Unit, 00168 Roma, Italy.
Piergiorgio BrunoFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
Raffaele LandolfiFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.
Andrea FlexFondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Roma, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2019 novel coronavirus [2019-nCoV], which started to spread from December 2019 onwards, caused a global pandemic. Besides being responsible for the severe acute respiratory syndrome 2 [SARS-CoV-2], the virus can affect other organs causing various symptoms. A close relationship between SARS-CoV-2 and the cardiovascular system has been shown, demonstrating an epidemiological linkage between SARS-CoV-2 and cardiac injury. There are emerging data regarding possible direct myocardial damage by 2019-nCoV. In this review, the most important available evidences will be discussed to clarify the precise mechanisms of cardiovascular injury in SARS-CoV-2 patients, even if further researches are needed.

Indexed as

AnimalsBetacoronavirusCardiovascular DiseasesCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralSARS-CoV-2cardiovascular diseasesSARS-CoV-2

Identifiers

PMID33143371
PMCPMC7663579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.