Evidence map›Paper›PMID 33142991›Full record

ArticleViruses2020

The Antiviral Small-Interfering RNA Pathway Induces Zika Virus Resistance in Transgenic

Adeline E Williams, Irma Sanchez-Vargas, William R Reid, Jingyi Lin, Alexander W E Franz, Ken E Olson

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Adeline E WilliamsDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-8433-0060
Irma Sanchez-VargasDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.ORCID 0000-0002-1724-7005
William R ReidDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Jingyi LinDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.
Alexander W E FranzDepartment of Veterinary Pathobiology, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-3243-8408
Ken E OlsonDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA.
Colorado State University · USUniversity of Missouri · US

Funding

Engineering resistance to Zika virus in Aedes aegypti for Cas9 driven population modificationR01AI130085 · NIAID · COLORADO STATE UNIVERSITY · PI OLSON, KENNETH E · 2018 to 2021
$2.7M
NIAID NIH HHS R01 AI130085
6 · The paper itself

Abstract

The resurgence of arbovirus outbreaks across the globe, including the recent Zika virus (ZIKV) epidemic in 2015-2016, emphasizes the need for innovative vector control methods. In this study, we investigated ZIKV susceptibility to transgenic

Indexed as

Genome, ViralAedesAnimalsAnimals, Genetically ModifiedCRISPR-Cas SystemsDisease ResistanceDisease SusceptibilityFemaleMaleMosquito VectorsRNA, Small InterferingSalivaViral LoadVirus ReplicationZika VirusZika Virus InfectionRNA, Small InterferingAedes aegyptiantiviral immunityarbovirusCRISPR/Cas9RNAisiRNAstransgenesisZika virus

Identifiers

PMID33142991
PMCPMC7692394
OpenAlexW3097389137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.