Evidence map›Paper›PMID 33142989›Full record

ReviewBiomedicines2020

Osmotic Adaptation by Na

Danah Muhanna, Shanvanth R Arnipalli, Shashi B Kumar, Ouliana Ziouzenkova

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. ACE2: Friend or Foe in Post-COVID-19 Neurodegeneration?International journal of molecular sciences · 2025
    Review
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  11. Air Pollution and COVID-19: A Possible Dangerous Synergy for Male Fertility.International journal of environmental research and public health · 2021
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Danah MuhannaDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, USA.
Shanvanth R ArnipalliDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, USA.
Shashi B KumarDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, USA.
Ouliana ZiouzenkovaDepartment of Human Sciences, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2449-2591
The Ohio State University · US

Funding

University of Iowa Clinical and Translational Science Program (TL1)UL1RR025755 · NCRR · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA D · 2008 to 2011
$26.3M
NCRR NIH HHS UL1RR025755
6 · The paper itself

Abstract

COVID-19 symptoms, including hypokalemia, hypoalbuminemia, ageusia, neurological dysfunctions, D-dimer production, and multi-organ microthrombosis reach beyond effects attributed to impaired angiotensin-converting enzyme 2 (ACE2) signaling and elevated concentrations of angiotensin II (Ang II). Although both SARS-CoV (Severe Acute Respiratory Syndrome Coronavirus) and SARS-CoV-2 utilize ACE2 for host entry, distinct COVID-19 pathogenesis coincides with the acquisition of a new sequence, which is homologous to the furin cleavage site of the human epithelial Na

Indexed as

angiotensincoagulationhypertensioninflammationorgan failurethrombosistonicitytransportersvirus

Identifiers

PMID33142989
PMCPMC7693583
OpenAlexW3096299130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.