Evidence map›Paper›PMID 33142949›Full record

ArticleInternational journal of molecular sciences2020

Ethanol Intoxication Alleviates the Inflammatory Response of Remote Organs to Experimental Traumatic Brain Injury.

Baolin Xu, Akila Chandrasekar, Florian Olde Heuvel, Maciej Powerski, Aleksander Nowak, Laurens Noack, Jazan Omari, Markus Huber-Lang, Francesco Roselli, Borna Relja

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Baolin XuExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Akila ChandrasekarDepartment of Neurology, Ulm University, 89081 Ulm, Germany.
Florian Olde HeuvelDepartment of Neurology, Ulm University, 89081 Ulm, Germany.
Maciej PowerskiExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Aleksander NowakExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Laurens NoackExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.ORCID 0000-0002-9496-9909
Jazan OmariExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Markus Huber-LangInstitute of Clinical and Experimental Trauma-Immunology, University Hospital Ulm, Ulm University, 89081 Ulm, Germany.
Francesco RoselliGerman Center for Neurodegenerative Diseases (DZNE)-Ulm, 89081 Ulm, Germany.ORCID 0000-0001-9935-6899
Borna ReljaExperimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University, 39120 Magdeburg, Germany.
Otto-von-Guericke-Universität Magdeburg · DEUniversität Ulm · DEGerman Center for Neurodegenerative Diseases · DEUniversity Hospital Ulm · DE

Funding

BMBF 01EW1705ADeutsche Forschungsgemeinschaft RE 3304/8-1DFG RO-5004/8-1DFG RO5004/9-1Radala Foundation nn
6 · The paper itself

Abstract

Traumatic brain injury (TBI) may cause damage to distant organs. Acute ethanol intoxication (EI) induces complex local and systemic anti-inflammatory effects and influences the early outcomes of traumatized patients. Here, we evaluated its effects on the BI-induced expression of local inflammatory mediators in the trauma-remote organs the lungs and liver. Male mice were exposed to ethanol as a single oral dose (5g·kg

Indexed as

Alcoholic IntoxicationAnimalsBrain Injuries, TraumaticCentral Nervous System DepressantsCytokinesDisease Models, AnimalEthanolHMGB1 ProteinInflammationInterleukin-10Interleukin-1betaLiverLungMaleMiceReceptor for Advanced Glycation End ProductsCentral Nervous System DepressantsCytokinesEthanolHMGB1 ProteinIL1B protein, mouseInterleukin-10Interleukin-1betaReceptor for Advanced Glycation End ProductsalcoholcytokinesinflammationliverlungTBI

Identifiers

PMID33142949
PMCPMC7663496
OpenAlexW3095352622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.