Evidence map›Paper›PMID 33142858›Full record

ArticleMaterials (Basel, Switzerland)2020

Molecular Fingerprint Imaging to Identify Dental Caries Using Raman Spectroscopy.

Nao Miyamoto, Tetsuya Adachi, Francesco Boschetto, Matteo Zanocco, Toshiro Yamamoto, Elia Marin, Shota Somekawa, Ryutaro Ashida, Wenliang Zhu, Narisato Kanamura and 2 more

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Photonic Methods for the Assessment of Lesion Activity.Diagnostics (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. In Situ Raman Analysis of Biofilm Exopolysaccharides Formed inInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Special Issue: Advances in Dental Bio-Nanomaterials.Materials (Basel, Switzerland) · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Nao MiyamotoDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.ORCID 0000-0001-6343-0890
Tetsuya AdachiDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.ORCID 0000-0001-5224-7812
Francesco BoschettoDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.
Matteo ZanoccoCeramic Physics Laboratory, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.
Toshiro YamamotoDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.
Elia MarinDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.ORCID 0000-0002-0981-7821
Shota SomekawaShinSei Co., Ltd., Hiramori Okubo-cho, Uji-shi, Kyoto 611-0033, Japan.
Ryutaro AshidaShinSei Co., Ltd., Hiramori Okubo-cho, Uji-shi, Kyoto 611-0033, Japan.
Wenliang ZhuCeramic Physics Laboratory, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.
Narisato KanamuraDepartment of Dental Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kamigyo-ku, Kyoto 602-8566, Japan.
Ichiro NishimuraDivision of Oral Biology and Medicine, The Jane and Jerry Weintraub Center for Re-constructive Biotechnology, UCLA School of Dentistry, Los Angeles, CA 90095, USA.ORCID 0000-0002-3749-9445
Giuseppe PezzottiCeramic Physics Laboratory, Kyoto Institute of Technology, Sakyo-ku, Matsugasaki, Kyoto 606-8585, Japan.
Kyoto Institute of Technology · JPKyoto Prefectural University of Medicine · JPTaisei (Japan) · JPFraunhofer USA · US

Funding

The Strategic Foundational Technology Improvement Support Operation of the Japanese Government 3130005002942, 6130001039102
6 · The paper itself

Abstract

Tooth loss impairs mastication, deglutition and esthetics and affects systemic health through nutritional deficiency, weight loss, muscle weakness, delayed wound healing, and bone fragility. Approximately 90% of tooth loss is due to dental caries and periodontal disease. Accordingly, early treatment of dental caries is essential to maintaining quality of life. To date, the clinical diagnosis of dental caries has been based on each dentist's subjective assessment, but this visual method lacks objectivity. To improve diagnostic ability, highly sensitive quantitative methods have been developed for the diagnosis and prevention of dental caries and are gradually becoming a mandatory item in modern dentistry. High-resolution Raman spectroscopy is a suitable tool for recognizing the subtle structural changes that occur in dental enamel in already developed or, more importantly, incipient dental caries. Raman analysis could soon emerge as a breakthrough in dentistry because of its high diagnostic sensitivity. In this study, we build upon our previous findings in a new analysis of dental caries using Raman spectroscopy imaging and discuss the possibility of using Raman photonic imaging in support of objective diagnostics in dentistry. Our findings support the Raman method of caries detection in comparison with other conventional or new approaches.

Indexed as

cariesdentistrylaser fluorescenceRaman spectroscopy

Identifiers

PMID33142858
PMCPMC7662967
OpenAlexW3095477411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.