Evidence map›Paper›PMID 33142697›Full record

ArticleLife (Basel, Switzerland)2020

Telomere Instability in Lynch Syndrome Families Leads to Some Shorter Telomeres in

M Carmen Garrido-Navas, Frances Tippins, Julian Barwell, Jonathan Hoffman, Veryan Codd, Nicola J Royle

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. GermlineGenetics in medicine open · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

M Carmen Garrido-NavasDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.ORCID 0000-0002-3965-0663
Frances TippinsDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Julian BarwellDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Jonathan HoffmanClinical Genetics Unit, Birmingham Women's Hospital, Birmingham B15 2TG, UK.
Veryan CoddDepartment of Cardiovascular Sciences, University of Leicester, BHF Cardiovascular Research Centre, Glenfield Hospital, Leicester LE3 9QP, UK.
Nicola J RoyleDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.ORCID 0000-0003-1174-6329
University of Leicester · GBBirmingham Women's Hospital · GB

Funding

Cancer Research UK Leicester Centre Development FundingMedical Research Council G0500336Univeristy of Leicester PhD studentship
6 · The paper itself

Abstract

Lynch syndrome (LS) is an inherited predisposition to early onset of various cancers, caused by mutation in a DNA mismatch repair (MMR) gene. In heterozygous MMR

Indexed as

DNA mismatch repairLynch syndromeMLH1MSH2telomeres

Identifiers

PMID33142697
PMCPMC7692680
OpenAlexW3097516250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.