Evidence map›Paper›PMID 33142431›Full record

ReviewBioorganic chemistry2020

A perspective on potential target proteins of COVID-19: Comparison with SARS-CoV for designing new small molecules.

Devendra Kumar, Gaurav Chauhan, Sourav Kalra, Bhupinder Kumar, Manjinder Singh Gill

Open access · greenAbstract readComparative StudyReview
In one paragraph

Review in Bioorganic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
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  9. RSC advances · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Devendra KumarDepartment of Pharmaceutical Chemistry, ISF College of Pharmacy, Ghal Kalan, G.T Road, Moga, Punjab 142001, India.
Gaurav ChauhanSchool of Engineering and Sciences, Tecnologico de Monterrey, Av. Eugenio Garza Sada 2501 Sur, 64849 Monterrey, Nuevo León, Mexico.
Sourav KalraDepartment of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research, SAS Nagar, Sector 67, Mohali, Punjab 160062, India.
Bhupinder KumarDepartment of Pharmaceutical Chemistry, ISF College of Pharmacy, Ghal Kalan, G.T Road, Moga, Punjab 142001, India. Electronic address: bhupinderkumar@isfcp.org.
Manjinder Singh GillDepartment of Pharmaceutical Technology (Process Chemistry), National Institute of Pharmaceutical Education and Research, SAS Nagar, Sector 67, Mohali, Punjab 160062, India. Electronic address: msingh@niper.ac.in.
Indo Soviet Friendship College of Pharmacy · INNational Institute of Pharmaceutical Education and Research · INTecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 (COVID-19) epidemic has created an unprecedented medical and economic crisis all over the world. SARS-CoV-2 is found to have more contagious character as compared to MERS-CoV and is spreading in a very fast manner all around the globe. It has affected over 31 million people all over the world till date. This virus shares around 80% of genome similarity with SARS-CoV. In this perspective, we have explored three major targets namely; SARS-CoV-2 spike (S) protein, RNA dependent RNA polymerase, and 3CL or M

Indexed as

Amino Acid SequenceAnimalsAntiviral AgentsBinding SitesCOVID-19COVID-19 Drug TreatmentDrug RepositioningHumansProtein BindingSARS-CoV-2Severe acute respiratory syndrome-related coronavirusViral Nonstructural ProteinsViral Structural ProteinsAntiviral AgentsViral Nonstructural ProteinsViral Structural Proteins3CL or Mpro ProteaseClinical trialsCOVID-19RNA dependent RNA polymeraseSARS-CoV-2SARS-CoV-2 spike (S) protein

Identifiers

PMID33142431
PMCPMC7524440
OpenAlexW3091755609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.