Evidence map›Paper›PMID 33142177›Full record

Observational studyThe American journal of emergency medicine2020

The management of the poisoned patient using a novel emergency department-based resuscitation and critical care unit (ResCCU).

Anita Mudan, Jennifer S Love, John C Greenwood, Carolyn Stickley, Victoria L Zhou, Frances S Shofer, David H Jang

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in The American journal of emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Anita MudanDepartment of Emergency Medicine, University of California San Francisco, United States.
Jennifer S LoveDepartment of Emergency Medicine, Oregon Health & Science University, United States.
John C GreenwoodDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Carolyn StickleyDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Victoria L ZhouDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
Frances S ShoferDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.
David H JangDepartment of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address: david.jang@uphs.upenn.edu.
University of Pennsylvania · USOregon Health & Science University · USUniversity of California, San Francisco · US

Funding

Abnormal Mitochondrial Bioenergetic and Motility Signatures in Human Blood Cells as Indices of Acute Poisoning in PatientsK08HL136858 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI JANG, DAVID H · 2018 to 2021
$675k
Mitochondrial-Directed Therapy in Carbon Monoxide PoisoningR21ES031243 · NIEHS · UNIVERSITY OF PENNSYLVANIA · PI JANG, DAVID H · 2020 to 2021
$465k
Development of a Porcine Model of Carbon Monoxide Poisoning to Evaluate Cardiac and Mitochondrial DysfunctionR03HL154232 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI JANG, DAVID H · 2020 to 2021
$150k
NHLBI NIH HHS K08 HL136858NHLBI NIH HHS R03 HL154232NIEHS NIH HHS R21 ES031243
6 · The paper itself

Abstract

objectivesThe Resuscitation & Critical Care Unit (ResCCU) is a novel ED-based ICU designed to provide early critical care services. This study sought to identify characteristics of poisoned patients treated in the ResCCU.

methodsWe conducted a retrospective, single-center case study of poisoned patients over the age of 18 years old over a 16-month period. Patient demographics, drug concentrations, and severity of illness scores were extracted from electronic medical records. Patients were divided into two groups, those who required short term ICU level care (< 24 h) and prolonged ICU care (> 24 h).

resultsA total of 58 ED visits with a tox-related illness were analyzed. There were 24 women (41%) and 34 men (59%). There were 42 patients (72%) who required short term ICU level care and 16 patients (28%) who required prolonged ICU care. In the short-term ICU group, 13 patients (31%) were discharged home directly from the ResCCU, 29 patients (69%) were sent to the inpatient floor, and 1 of the admitted floor patients expired. There were no patients admitted to the floor that required a step-up to the inpatient ICU. 56 patients (97%) were alive at post-admit day 7 and 28, and only 8 (14%) were re-admitted within 30 days.

conclusionsPatients who were treated in the ED-based ICU for toxicology-related illnesses were frequently able to be either discharged home or admitted to a regular floor after their initial stabilization and treatment, and none that were sent to the floor required an ICU step-up.

Indexed as

AdolescentAdultAgedAPACHECohort StudiesCritical CareDisease ManagementEmergency Service, HospitalFemaleHospitalizationHumansLength of StayMaleMiddle AgedOrgan Dysfunction ScoresPoisoningEmergency medicineICUToxicology

Identifiers

PMID33142177
PMCPMC7704670
OpenAlexW3037644870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.