Evidence map›Paper›PMID 33141660›Full record

ArticleParasite (Paris, France)2020

Asymptomatic Cryptosporidium infections in ewes and lambs are a source of environmental contamination with zoonotic genotypes of Cryptosporidium parvum.

Léa Bordes, Pauline Houert, Damien Costa, Loïc Favennec, Corinne Vial-Novella, Francis Fidelle, Christelle Grisez, Françoise Prévot, Philippe Jacquiet, Romy Razakandrainibe

Open access · goldAbstract read
In one paragraph

Article in Parasite (Paris, France), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. The global prevalence ofParasitology · 2022
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  6. First nationwide investigation ofCurrent research in parasitology & vector-borne diseases · 2025
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  7. Investigating genetic diversity withinCurrent research in parasitology & vector-borne diseases · 2025
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  8. A review of recentCurrent research in parasitology & vector-borne diseases · 2025
    Review
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  10. Molecular Detection and Distribution ofTransboundary and emerging diseases · 2023
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Léa BordesIHAP, UMT Pilotage de la Santé des Ruminants, Université de Toulouse, INRAE, ENVT, 31076 Toulouse, France.ORCID 0000-0002-2286-9925
Pauline HouertIHAP, UMT Pilotage de la Santé des Ruminants, Université de Toulouse, INRAE, ENVT, 31076 Toulouse, France.
Damien CostaCentre Hospitalier Universitaire, Centre National de Référence - Laboratoire Expert des Cryptosporidioses, 76031 Rouen, France.
Loïc FavennecCentre Hospitalier Universitaire, Centre National de Référence - Laboratoire Expert des Cryptosporidioses, 76031 Rouen, France.
Corinne Vial-NovellaCentre Départemental pour l'Elevage Ovin, Quartier Ahetzia, 64130 Ordiarp, France.
Francis FidelleCentre Départemental pour l'Elevage Ovin, Quartier Ahetzia, 64130 Ordiarp, France.
Christelle GrisezIHAP, UMT Pilotage de la Santé des Ruminants, Université de Toulouse, INRAE, ENVT, 31076 Toulouse, France.
Françoise PrévotIHAP, UMT Pilotage de la Santé des Ruminants, Université de Toulouse, INRAE, ENVT, 31076 Toulouse, France.
Philippe JacquietIHAP, UMT Pilotage de la Santé des Ruminants, Université de Toulouse, INRAE, ENVT, 31076 Toulouse, France.
Romy RazakandrainibeCentre Hospitalier Universitaire, Centre National de Référence - Laboratoire Expert des Cryptosporidioses, 76031 Rouen, France.
École Nationale Vétérinaire de Toulouse · FRLaboratoire National de Référence · MAInstitut de l’Elevage · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protozoan parasites of the Cryptosporidium genus cause severe cryptosporidiosis in newborn lambs. However, asymptomatic infections also occur frequently in lambs and ewes. In sheep, the most commonly detected Cryptosporidium species are C. ubiquitum, C. xiaoi and C. parvum. Due to a lack of relevant information about such infections in France, we investigated the situation on five dairy sheep farms in the Pyrénées-Atlantiques Department in south-western France in December 2017. Individual fecal samples were collected from 79 female lambs (5-17 days old) and their mothers (72 ewes). Oocysts were screened using Heine staining before and after Bailenger concentrations. Cryptosporidium species identification and genotyping were performed using real-time PCR and gp60 gene sequencing. No cases of clinical cryptosporidiosis were observed in the 79 lambs. Microscopically, Cryptosporidium spp. oocysts were observed in only one lamb on one farm (prevalence 1.3%) and one ewe on another farm (prevalence 1.4%). By contrast, Cryptosporidium spp. DNA was detected in 17 ewes (prevalence ranging from 10.5% to 50% depending on the farm) and in 36 lambs (prevalence ranging from 0% to 77.8% depending on the farm). Only zoonotic Cryptosporidium parvum IId and IIa genotypes were identified when genotyping was possible. Cryptosporidium ubiquitum and C. xiaoi were detected on one and three farms, respectively. We conclude that healthy young lambs and their mothers during the peripartum period could be a source of environmental contamination with oocysts.

Indexed as

Asymptomatic InfectionsCryptosporidiosisCryptosporidium parvumGenotypeSheep DiseasesAnimalsFecesFemaleFrancePrevalenceSheepAsymptomatic infectionCryptosporidium parvumEweLambPCRZoonotic genotypes

Identifiers

PMID33141660
PMCPMC7608980
OpenAlexW3097735370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.