Evidence map›Paper›PMID 33141263›Full record

ArticleEuropean journal of applied physiology2021

Lung abnormalities do not influence aerobic capacity in school children born preterm.

Christopher A O'Dea, Karla Logie, Andrew C Wilson, J Jane Pillow, Conor Murray, Georgia Banton, Shannon J Simpson, Graham L Hall, Andrew Maiorana

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In one paragraph

Article in European journal of applied physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Physiological responses to exercise in survivors of preterm birth: a meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Christopher A O'DeaRespiratory Medicine, Perth Children's Hospital, Perth, WA, Australia.ORCID http://orcid.org/0000-0001-8378-8507
Karla LogieTelethon Kids Institute, Perth, WA, Australia.
Andrew C WilsonRespiratory Medicine, Perth Children's Hospital, Perth, WA, Australia.
J Jane PillowDivision of Paediatrics and Child Health, Medical School, University of Western Australia, Perth, WA, Australia.
Conor MurrayDiagnostic Imaging, Perth Children's Hospital, Perth, WA, Australia.
Georgia BantonTelethon Kids Institute, Perth, WA, Australia.
Shannon J SimpsonSchool of Physiotherapy and Exercise Science, Curtin University, GPO Box U1987, Perth, WA, 6845, Australia.
Graham L HallRespiratory Medicine, Perth Children's Hospital, Perth, WA, Australia.
Andrew MaioranaSchool of Physiotherapy and Exercise Science, Curtin University, GPO Box U1987, Perth, WA, 6845, Australia. A.Maiorana@curtin.edu.au.ORCID http://orcid.org/0000-0002-0681-1707
The Kids Research Institute Australia · AUCurtin University · AUPrincess Margaret Hospital for Children · AUThe University of Western Australia · AU

Funding

National health and medical research council APP513730National Health and Medical Research Council APP1025550National Health and Medical Research Council APP1073301National Health and Medical Research Council APP1077691
6 · The paper itself

Abstract

purposeChildren born preterm have impaired lung function and altered lung structure. However, there are conflicting reports on how preterm birth impacts aerobic exercise capacity in childhood. We aimed to investigate how neonatal history and a diagnosis of bronchopulmonary dysplasia (BPD) impact the relationship between function and structure of the lung, and aerobic capacity in school-aged children born very preterm.

methodsPreterm children (≤ 32 w completed gestation) aged 9-12 years with (n = 38) and without (n = 35) BPD, and term-born controls (n = 31), underwent spirometry, lung volume measurements, gas transfer capacity, a high-resolution computer tomography (CT) scan of the chest, and an incremental treadmill exercise test.

resultsChildren born preterm with BPD had an elevated breathing frequency to tidal volume ratio compared to term controls (76% vs 63%, p = 0.002). The majority (88%) of preterm children had structural changes on CT scan. There were no differences in peak V̇O

conclusionChildren born preterm have impaired lung function, and a high prevalence of structural lung abnormalities. However, abnormal lung function and structure do not appear to impact on the aerobic exercise capacity of preterm children at school age.

Indexed as

Bronchopulmonary DysplasiaChildExerciseExercise TestExercise ToleranceFemaleHumansLungMalePremature BirthRespirationSchoolsSpirometryTidal VolumeBronchopulmonary dysplasiaExercise and lung diseaseImaging/CTLung physiologyPaediatric lung disease

Identifiers

PMID33141263
OpenAlexW3095080484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.