Evidence map›Paper›PMID 33140999›Full record

ArticleJournal of feline medicine and surgery2021

Subcutaneous administration of triamcinolone as part of the management of feline eosinophilic keratoconjunctivitis.

Danica R Lucyshyn, Kathryn L Good, Kelly E Knickelbein, Maggie W Chang, Ann R Strøm, Steven R Hollingsworth, Sara M Thomasy, Brian C Leonard, Lionel Sebbag, K Tomo Wiggans and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of feline medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Diagnostic Ophthalmology.The Canadian veterinary journal = La revue veterinaire canadienne · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Danica R LucyshynDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.ORCID https://orcid.org/0000-0001-7054-3869
Kathryn L GoodDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.
Kelly E KnickelbeinVeterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA.
Maggie W ChangSchool of Veterinary Medicine, University of California-Davis, Davis, CA, USA.
Ann R StrømVeterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA.ORCID https://orcid.org/0000-0003-3878-160X
Steven R HollingsworthDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.
Sara M ThomasyDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.
Brian C LeonardDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.ORCID https://orcid.org/0000-0003-2080-8480
Lionel SebbagVeterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA.ORCID https://orcid.org/0000-0002-0103-0127
K Tomo WiggansVeterinary Medical Teaching Hospital, University of California-Davis, Davis, CA, USA.
David J MaggsDepartment of Surgical and Radiological Sciences, University of California-Davis, Davis, CA, USA.ORCID https://orcid.org/0000-0001-6537-4335
University of California, Davis · USVeterinary Medical Teaching Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this retrospective case-control study was to report the efficacy of subcutaneous triamcinolone as part of a regimen for feline eosinophilic keratoconjunctivitis (FEK).

methodsRecords and clinical photographs were reviewed and lesions semiquantitatively graded for cats with cytologically confirmed FEK. Clinical data were compared between a study population of nine cats (11 eyes) treated with, and a reference population of seven cats (eight eyes) treated without, a median of 0.11 mg/kg (range 0.10-0.20 mg/kg) of triamcinolone acetonide subcutaneously.

resultsBreed, sex, age and prevalence of corneal ulceration at presentation; corneal disease severity before and at the initiation of immunomodulation; and duration of antiviral treatment before immunomodulation did not differ significantly between populations ( CONCLUSIONS AND RELEVANCE: In otherwise healthy cats with FEK, subcutaneous administration of triamcinolone appears to be well tolerated and as efficacious as conventional topical immunomodulatory therapies. It may be especially useful in ulcerated eyes where topical immunomodulation is contraindicated.

Indexed as

Cat DiseasesCorneal DiseasesKeratoconjunctivitisAnimalsCase-Control StudiesCatsRetrospective StudiesTriamcinolone AcetonideTriamcinolone Acetonideantiviral drugscorneal cytologycorticosteroidshypersensitivityKeratitis

Identifiers

PMID33140999
PMCPMC10741297
OpenAlexW3097259298

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.