Evidence map›Paper›PMID 33140915›Full record

ArticleJournal of applied clinical medical physics2020

A retrospective analysis of setup and intrafraction positional variation in stereotactic radiotherapy treatments.

Micah Barnes, Adam Yeo, Kenton Thompson, Claire Phillips, Tomas Kron, Nicholas Hardcastle

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Significance of positional correction of planned couch angles with the ExacTrac system.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Article
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  4. Surface guided radiation therapy with an innovative open-face mask and mouth bite: patient motion management in brain stereotactic radiotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
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  7. Synthetic CTs for MRI-only brain RT treatment: integration of immobilization systems.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Micah BarnesDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-8691-0616
Adam YeoDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-9725-0668
Kenton ThompsonDepartment of Radiation Therapy Services, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-1965-0885
Claire PhillipsDepartment of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0001-7215-8729
Tomas KronDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0002-5189-4046
Nicholas HardcastleDepartment of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0001-7796-8472
Peter MacCallum Cancer Centre · AUThe University of Melbourne · AUAustralian Nuclear Science and Technology Organisation · AU

Funding

The Eric and Elizabeth Gross Foundation
6 · The paper itself

Abstract

purposeThe aim of this study was to provide a comprehensive assessment of patient intrafraction motion in linac-based frameless stereotactic radiosurgery (SRS) and radiotherapy (SRT).

methodsA retrospective review was performed on 101 intracranial SRS/SRT patients immobilized with the Klarity stereotactic thermoplastic mask (compatible with the Brainlab frameless stereotactic system) and aligned on a 6 Degree of Freedom (DoF) couch with the Brainlab ExacTrac image guidance system. Both pretreatment and intrafraction correction data are provided as observed by the ExacTrac system. The effects of couch angle and treatment duration on positioning outcomes are also explored.

resultsInitial setup data for patients is shown to vary by up to ±4.18 mm, ±2.97°, but when corrected with a single x-ray image set with ExacTrac, patient positions are corrected to within ±2.11 mm, ±2.27°. Intrafraction patient motion is shown to be uniformly random and independent of both time and couch angle. Patient motion was also limited to within approximately 3 mm, 3° by the thermoplastic mask.

conclusionsOur results indicate that since patient intrafraction motion is unrelated to couch rotation and treatment duration, intrafraction patient monitoring in 6 DoF is required to minimize intracranial SRS/SRT margins.

Indexed as

Brain NeoplasmsRadiosurgeryHumansImaging, Three-DimensionalParticle AcceleratorsPatient PositioningRadiotherapy Planning, Computer-AssistedRadiotherapy Setup ErrorsRetrospective StudiesRotationExacTracIGRTimage guidanceintrafraction motionpatient positionSRSSRTthermoplastic mask

Identifiers

PMID33140915
PMCPMC7769413
OpenAlexW3096135506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.