Evidence map›Paper›PMID 33140912›Full record

ArticleCancer medicine2021

Skeletal muscle and adipose tissue changes in the first phase of treatment of pediatric solid tumors.

Lenat Joffe, Wei Shen, Grace Shadid, Zhezhen Jin, Elena J Ladas

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Body Composition at Diagnosis and Early Response in Pediatric Hodgkin Lymphoma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  7. Observational
  8. Metabolic Implications of Childhood Cancer.Current pediatrics reports · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Lower subcutaneous fat index predicts bone metastasis in breast cancer.Cancer biomarkers : section A of Disease markers · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lenat JoffeDepartment of Pediatrics, Division of Pediatric Hematology/ Oncology/ Stem Cell Transplant, Columbia University Irving Medical Center, New York, NY, USA.
Wei ShenDepartment of Pediatric Gastroenterology, Hepatology and Nutrition, Institute of Human Nutrition; and MR Research Center, Columbia University Irving Medical Center, New York, NY, USA.
Grace ShadidInstitute of Human Nutrition, Columbia University Irving Medical Center, New York, NY, USA.
Zhezhen JinDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.
Elena J LadasDepartment of Pediatrics, Division of Pediatric Hematology/ Oncology/ Stem Cell Transplant, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0001-5077-5582
Columbia University Irving Medical Center · USColumbia University · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Training Program in Cancer-related Population SciencesT32CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I., TERRY, MARY BETH · 2017 to 2021
$1.1M
NCI NIH HHS T32 CA094061NIDDK NIH HHS P30 DK026687
6 · The paper itself

Abstract

Body composition is increasingly recognized as an important factor in cancer outcomes. Use of computed tomography (CT) in cancer care provides the opportunity to accurately quantify whole-body lean and adipose tissues from images at the third lumbar spine. We sought to substantiate the use of routinely captured, single-slice chest CT images at the thoracic level for evaluation of skeletal muscle, residual lean tissue, and adiposity among pediatric solid tumor patients. We performed a retrospective analysis among children who underwent treatment for a solid tumor at Columbia University Irving Medical Center. Skeletal muscle (SM), residual lean tissue (RLT), and adipose tissue cross-sectional areas (cm

Indexed as

Body CompositionTomography, X-Ray ComputedAdiposityAdolescentAge FactorsBody Mass IndexChildChild Nutritional Physiological PhenomenaChild, PreschoolFemaleHumansInfantIntra-Abdominal FatMaleMuscle, SkeletalNeoplasmsbody compositionchildhood cancernutritionnutritional statuspediatric cancersolid tumors

Identifiers

PMID33140912
PMCPMC7826460
OpenAlexW3095600026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.