Evidence map›Paper›PMID 33140588›Full record

ArticleJournal of Korean medical science2020

Incremental Predictive Value of Plasma Renin Activity as a Prognostic Biomarker in Patients with Heart Failure.

Bo Eun Park, Dong Heon Yang, Hyeon Jeong Kim, Yoon Jung Park, Hong Nyun Kim, Se Yong Jang, Myung Hwan Bae, Jang Hoon Lee, Hun Sik Park, Yongkeun Cho and 1 more

Abstract read
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bo Eun ParkDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-5245-9863
Dong Heon YangDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-1646-6126
Hyeon Jeong KimDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-3496-3142
Yoon Jung ParkDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-5132-226X
Hong Nyun KimCardiology Center, Kyungpook National University Chilgok Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-9903-1848
Se Yong JangDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-4981-879X
Myung Hwan BaeDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-7677-4895
Jang Hoon LeeDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-7101-0236
Hun Sik ParkDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-7138-1494
Yongkeun ChoDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0001-9455-0190
Shung Chull ChaeDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0002-9871-6976

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association of N-terminal pro-B type natriuretic peptide (NT-proBNP) and plasma renin activity (PRA) for the prognosis of the patients with acute heart failure (HF) has not been fully investigated. This study aimed to determine the association between NT-proBNP and PRA and to investigate the incremental value of PRA to NT-proBNP for predicting long term prognosis in patients with acute HF.

methodsThree hundred and ninety-six patients (mean age, 64.7 ± 15.9 years; 46.5% female) presenting with acute HF were enrolled between December 2004 and July 2013. Patients with newly diagnosed HF as well as patients with acute exacerbated chronic HF were included. The prognosis was assessed with the composite event of all-cause mortality and readmission for HF during a 2-year follow-up period.

resultsThe etiology of HF was ischemic in 116 (29.3%) patients. In a Cox proportional hazards model, log-transformed PRA (hazard ratio [HR], 1.205;

conclusionPRA could provide incremental predictive value to NT-proBNP for predicting long term prognosis in patients with acute HF.

Indexed as

AgedAged, 80 and overArea Under CurveBiomarkersFemaleHeart FailureHumansKaplan-Meier EstimateLeukocyte CountMaleMiddle AgedNatriuretic Peptide, BrainPatient ReadmissionPeptide FragmentsPrognosisProportional Hazards ModelsBiomarkersNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)ReninHeart FailureNatriuretic PeptidesPrognosisRenin

Identifiers

PMID33140588
PMCPMC7606887

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.