Evidence map›Paper›PMID 33140519›Full record

ArticleAddiction (Abingdon, England)2021

Availability of buprenorphine/naloxone films and naloxone nasal spray in community pharmacies in Texas, USA.

Lucas G Hill, Lindsey J Loera, Kirk E Evoy, Mandy L Renfro, Sorina B Torrez, Claire M Zagorski, Joshua C Perez, Shaun M Jones, Kelly R Reveles

Abstract read
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Article in Addiction (Abingdon, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Price Sensitivity and Information Barriers to the Take-Up of Naloxone.American economic journal. Economic policy · 2024
    Article
  5. Article
  6. Article
  7. Observational
  8. Assessing suboxone access in community pharmacies: Secret shopper model.Exploratory research in clinical and social pharmacy · 2023
    Article
  9. Article
  10. Factors in rural community buprenorphine dispensing.Exploratory research in clinical and social pharmacy · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. A content review of buprenorphine training programs for pharmacists.Exploratory research in clinical and social pharmacy · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Lucas G HillCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0001-5958-0159
Lindsey J LoeraCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-7969-5209
Kirk E EvoyCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0003-0913-7145
Mandy L RenfroCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-2833-3179
Sorina B TorrezCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-3888-3457
Claire M ZagorskiCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-4636-864X
Joshua C PerezCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-1107-289X
Shaun M JonesDepartment of Psychiatry and Behavioral Sciences, University of Texas Health San Antonio, Austin, TX, USA.ORCID 0000-0002-8769-4919
Kelly R RevelesCollege of Pharmacy, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0001-8880-4879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPatients with opioid use disorder (OUD) must be able to obtain prescribed buprenorphine/naloxone films (BUP/NX) and naloxone nasal spray (NNS) from a pharmacy promptly to reduce risk for a recurrence of use and subsequent morbidity and mortality. Telephone audits have identified concerning gaps in availability of NNS within US pharmacies, but the availability of BUP/NX has not been rigorously evaluated. This study estimated the availability of BUP/NX and NNS in the US state of Texas and compared availability by pharmacy type and metropolitan status.

designA cross-sectional telephone audit with a secret shopper approach conducted from 18 May 2020 to 7 June 2020. Setting and Participants A random sample of 800 of 5078 (16%) community pharmacies licensed with the Texas State Board of Pharmacy. MEASUREMENTS: Primary outcomes included availability of a 1-week supply of generic BUP/NX 8/2 mg films and a single unit of NNS 4 mg, overall and by pharmacy type. Secondary outcomes included willingness and estimated time-frame to order BUP/NX if unavailable.

findingsData from 704 pharmacies (471 chain, 233 independent) were included for analyses. Of these, 34.1% of pharmacies (45.0% of chains versus 12.0% of independents, P < 0.0001) were willing and able to dispense a 1-week supply of generic BUP/NX and a single unit of NNS. BUP/NX alone was available in 42.2% of pharmacies (52.4% of chains versus 21.5% of independents, P < 0.0001). NNS alone was available in 60.1% of pharmacies (77.9% of chains versus 24.0% of independents, P < 0.0001). Of the 397 pharmacies with generic BUP/NX unavailable, 62.2% of pharmacies (73.9% of chains versus 48.0% of independents, P < 0.0001) indicated willingness to order.

conclusionsMost pharmacies in Texas do not appear to be willing and able to dispense prescribed buprenorphine/naloxone films and naloxone nasal spray to patients with opioid use disorder in a timely manner. Deficiencies in availability are markedly more pronounced in independent pharmacies compared with chain pharmacies.

Indexed as

BuprenorphineNaloxoneNarcotic AntagonistsPharmaciesCross-Sectional StudiesHealth Services AccessibilityHumansNasal SpraysTexasBuprenorphineNaloxoneNarcotic AntagonistsNasal SpraysBuprenorphinenaloxoneopioid-related disordersopioid substitution treatmentpharmacistspharmacy

Identifiers

PMID33140519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.