Evidence map›Paper›PMID 33140384›Full record

ArticleCardiology journal2022

Clinical outcomes of cryoballoon ablation for pulmonary vein isolation: Impact of intraprocedural heart rhythm.

Bruno Reissmann, Christian-H Heeger, Karena Opitz, Michael Schlüter, Peter Wohlmuth, Laura Rottner, Thomas Fink, Jin-Hong Gerds-Li, Shibu Mathew, Christine Lemes and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cardiology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Bruno ReissmannDepartment of Cardiology, University Heart Center Hamburg, Germany. b-reissmann@t-online.de.
Christian-H HeegerDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Karena OpitzDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Michael SchlüterAsklepios Proresearch, Hamburg, Germany.
Peter WohlmuthAsklepios Proresearch, Hamburg, Germany.
Laura RottnerDepartment of Cardiology, University Heart Center Hamburg, Germany.
Thomas FinkDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Jin-Hong Gerds-LiDepartment of Internal Medicine and Cardiology, German Heart Institute, Berlin, Germany.
Shibu MathewDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Christine LemesDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Tilman MaurerDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Feifan OuyangDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Karl-Heinz KuckDepartment of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
Andreas RilligDepartment of Cardiology, University Heart Center Hamburg, Germany.
Doreen SchöppenthauDepartment of Internal Medicine and Cardiology, German Heart Institute, Berlin, Germany.
Andreas MetznerDepartment of Cardiology, University Heart Center Hamburg, Germany.
Asklepios Klinik St. Georg · DEUniversität Hamburg · DEAsklepios · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current study sought to assess the impact of the intraprocedural heart rhythm (sinus rhythm [SR] vs. atrial fibrillation [AF]) on acute procedural characteristics, durability of pulmonary vein isolation (PVI) and long-term clinical outcomes of cryoballoon (CB) ablation.

methodsA total of 195 patients with symptomatic paroxysmal (n = 136) or persistent AF (n = 59) underwent CB-based PVI. Ablation procedures were either performed in SR (SR group; n = 147) or during AF (AF group; n = 48). Persistent AF was more frequent in the AF group than in the SR group (62% vs. 20%). All other patient baseline characteristics did not differ between the two groups.

resultsThe nadir temperature during the CB applications was significantly lower in the AF group than in patients in the SR group (-49 [interquartile range, -44; -54]°C vs. -47 [-42; -52]°C, p = 0.002). Median procedure and fluoroscopy times as well as the rate of real-time recordings were not different between the two groups. Repeat ablation for the treatment of atrial arrhythmia recurrence was performed in 60 patients (SR: 44 [30%] patients; AF: 16 [33%] patients), with a trend towards a lower rate of pulmonary vein reconnections in the AF group (p = 0.07). There was no difference in 3-year arrhythmia-free survival (p = 0.8).

conclusionsCryoballoon-based PVI during AF results in lower nadir balloon temperatures and a trend towards a higher durability of PVI as compared to procedures performed in SR. The rate of real-time PVI recordings was not affected by the intraprocedural heart rhythm.

Indexed as

Atrial FibrillationCatheter AblationCryosurgeryPulmonary VeinsHumansRecurrenceTreatment Outcomeclinical outcomescryoballoon ablationintraprocedural heart rhythmpulmonary vein isolation

Identifiers

PMID33140384
PMCPMC9550325
OpenAlexW3097096329

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.