SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021
Intracranial hemorrhage in coronavirus disease 2019 (COVID-19) patients.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Intracranial hemorrhages in patients with COVID-19: a systematic review of the literature, regarding six cases in an Amazonian population.Arquivos de neuro-psiquiatria · 2023Pooled it
- Characteristics of subarachnoid hemorrhage associated with COVID-19 infection: A systematic review and descriptive analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023Pooled it
- Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: incidence, risk factors, and pathogenesis - a systematic review and meta-analysis.F1000Research · 2021Pooled it
- In-hospital case-fatality after intracerebral hemorrhage in southern Iran: a single-center retrospective study.BMC neurology · 2026Observational
- Spontaneous Intracerebral Hemorrhages in the Post-COVID-19 Period without Classical Risk Factors: Clinical Characteristics and Outcomes.Journal of clinical practice and research · 2025Article
- Epidemiology, pathogenesis, and management of Coronavirus disease 2019-associated stroke.Frontiers of medicine · 2023Review
- Spontaneous subdural hematoma in a young COVID-19-confirmed patient without comorbidities: A case report.SAGE open medical case reports · 2023Article
- Intracranial hemorrhage detection in 3D computed tomography images using a bi-directional long short-term memory network-based modified genetic algorithm.Frontiers in neuroscience · 2023Article
- Subarachnoid Hemorrhage in Patients with SARS-CoV-2 Infection: Protocol for A Scoping Review.Brain sciences · 2022Article
- Differential proinflammatory activities of Spike proteins of SARS-CoV-2 variants of concern.Science advances · 2022Article
- Acute Neurologic Complications of COVID-19 and Postacute Sequelae of COVID-19.Critical care clinics · 2022Review
- Pregnancy and neurologic complications of COVID-19: A scoping review.Acta neurologica Scandinavica · 2022Article
- Extracorporeal membrane oxygenation (ECMO) in COVID-19 patients: a pocket guide for radiologists.La Radiologia medica · 2022Review
- Severe stroke in patients admitted to intensive care unit after COVID-19 infection: Pictorial essay of a case series.Brain hemorrhages · 2022Article
- Pathomechanisms and Treatment Implications for Stroke in COVID-19: A Review of the Literature.Life (Basel, Switzerland) · 2022Review
- Perioperative Complications of Patients with SARS-CoV-2 Infection in Neurosurgery.Journal of clinical medicine · 2022Article
- Spontaneous Intracerebral Hemorrhage (ICH) associated with pregnancy and SARS-CoV-2 infection: a case report.BMC pregnancy and childbirth · 2022Article
- SARS-CoV-2 infection increases risk of intracranial hemorrhage.Frontiers in human neuroscience · 2022Article
- Spontaneous intracerebral hemorrhage, initial computed tomography (CT) scan findings, clinical manifestations and possible risk factors.American journal of nuclear medicine and molecular imaging · 2022Article
- Concurrent intracranial infarct and intraventricular hemorrhage with spontaneous nontraumatic extradural hemorrhage in follow-up: An enigma of COVID-19-associated intracranial vasculopathy.Surgical neurology international · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmerging evidence suggests that a subset of coronavirus disease 2019 (COVID-19) patients may present with or develop cerebrovascular disease during the course of hospitalization. Whereas ischemic stroke in COVID-19 patients has been well described, data on intracranial hemorrhage (ICH) in these patients is still limited. We, therefore, conducted a rapid systematic review of current scientific literature to identify and consolidate evidence of ICH in COVID-19 patients.
methodsA systematic search of literature was conducted between November 1, 2019, and August 14, 2020, on PubMed and China National Knowledge Infrastructure (CNKI) to identify eligible studies.
resultsA total of 23 studies describing ICH in 148 COVID-19 patients were included. The pooled incidence of ICH in COVID-19 patients was 0.7% (95% CI 0.5-0.9), with low levels of inter-study heterogeneity observed (I
conclusionAlthough relatively uncommon among COVID-19 patients, ICH is associated with a high mortality rate. Early identification of patients at risk of developing ICH, particularly with comorbid conditions and on anticoagulant therapy, may be important to improve outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.