Evidence map›Paper›PMID 33140263›Full record

ArticleEJNMMI physics2020

Performance evaluation of fifth-generation ultra-high-resolution SPECT system with two stationary detectors and multi-pinhole imaging.

Jan V Hoffmann, Jan P Janssen, Takayuki Kanno, Takayuki Shibutani, Masahisa Onoguchi, Constantin Lapa, Jan-Peter Grunz, Andreas K Buck, Takahiro Higuchi

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Design and Evaluation of a Portable Pinhole SPECT System forDiagnostics (Basel, Switzerland) · 2025
    Article
  3. Review
  4. Radiation Detectors and Sensors in Medical Imaging.Sensors (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jan V HoffmannDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Strasse 6, 97080, Würzburg, Germany.
Jan P JanssenDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Strasse 6, 97080, Würzburg, Germany.
Takayuki KannoComprehensive Heart Failure Center, University Hospital Würzburg, Würzburg, Germany.
Takayuki ShibutaniDepartment of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Masahisa OnoguchiDepartment of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Constantin LapaNuclear Medicine, Medical Faculty, University of Augsburg, Augsburg, Germany.
Jan-Peter GrunzDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Andreas K BuckDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Strasse 6, 97080, Würzburg, Germany.
Takahiro HiguchiDepartment of Nuclear Medicine, University Hospital Würzburg, Oberdürrbacher Strasse 6, 97080, Würzburg, Germany. higuchi_t@ukw.de.ORCID http://orcid.org/0000-0001-9711-7835
Universitätsklinikum Würzburg · DEKanazawa University · JPOkayama University · JPUniversity of Augsburg · DE

Funding

DAAD PAJAKO fellowship
6 · The paper itself

Abstract

backgroundSmall-animal single-photon emission computed tomography (SPECT) systems with multi-pinhole collimation and large stationary detectors have advantages compared to systems with moving small detectors. These systems benefit from less labour-intensive maintenance and quality control as fewer prone parts are moving, higher accuracy for focused scans and maintaining high resolution with increased sensitivity due to focused pinholes on the field of view. This study aims to investigate the performance of a novel ultra-high-resolution scanner with two-detector configuration (U-SPECT5-E) and to compare its image quality to a conventional micro-SPECT system with three stationary detectors (U-SPECT

methodsThe new U-SPECT5-E with two stationary detectors was used for acquiring data with

resultsPeak sensitivity was 237 cps/MBq (XUHR-M), 847 cps/MBq (GP-M), 2054 cps/MBq (UHS-M) for U-SPECT5-E and 1710 cps/MBq (GP-M) for U-SPECT

conclusionsWhile uniformity and sensitivity are negatively affected by the absence of a third detector, the investigated U-SPECT5-E system with two stationary detectors delivers excellent spatial resolution and CNR comparable to the performance of an established three-detector-setup.

Indexed as

CollimatorMousePost-reconstruction filteringSmall-animal imaging, SPECT

Identifiers

PMID33140263
PMCPMC7606439
OpenAlexW3096669264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.