Evidence map›Paper›PMID 33140248›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Symptom experiences in post-treatment cancer survivors: associations with acceptance and commitment therapy constructs.

Ashley B Lewson, Shelley A Johns, Ellen Krueger, Kelly Chinh, Kelley M Kidwell, Catherine E Mosher

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07516314 (ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07516314 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

ACT to Reduce Morbidity and Mortality in Hematopoietic Stem Cell Transplant (HCT) Patients (ACTivate)

TypeinterventionalSponsorAnthony Sung, MDRan2026 to 2031Enrolled476ConditionsStem Cell Transplant PatientsArmsACTivate sessions
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Profiling of psychoneurological symptoms in newly diagnosed head and neck cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
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  8. Construction of a cutoff and fusion model of breast cancer patients in family: a grounded theory study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ashley B LewsonDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA. abeggin@iu.edu.
Shelley A JohnsDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Ellen KruegerDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Kelly ChinhDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
Kelley M KidwellDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Catherine E MosherDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
University of Indianapolis · USIndiana University – Purdue University Indianapolis · USUniversity of Michigan–Ann Arbor · US

Funding

Interdisciplinary Training in Cancer Prevention and ControlT32CA117865 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI Victoria Lee Champion, Catherine E Mosher · 2016 to 2026
$2.4M
Telephone Symptom Management for Advanced Lung Cancer Patients and CaregiversK07CA168883 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI MOSHER, CATHERINE E · 2013 to 2017
$682k
Research and Training for Behavioral Oncology InterventionsK05CA175048 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMPION, VICTORIA LEE · 2014 to 2018
$484k
NCI NIH HHS K05 CA175048NCI NIH HHS K05CA175048NCI NIH HHS K07 CA168883NCI NIH HHS K07CA168883NCI NIH HHS T32 CA117865NCI NIH HHS T32CA117865Walther Cancer Foundation 0175
6 · The paper itself

Abstract

purposeAcceptance and Commitment Therapy (ACT) has improved symptom and quality-of-life outcomes in pilot research with post-treatment cancer survivors. To further test the ACT model, the present study examined relationships between ACT constructs and subgroups of post-treatment survivors based on the severity of common symptoms.

methodsSurvivors who had completed primary treatment for stage I or II cancer (N = 203) participated in this one-time survey. Latent class analysis (LCA) was used to identify subgroups of survivors based on the severity of fatigue, sleep disturbance, pain, anxiety, and depressive symptoms. Multinomial logistic regressions employing Vermunt's 3-step approach were used to examine ACT constructs (e.g., mindfulness, acceptance, values progress) as correlates of survivor subgroups based on symptoms.

resultsThe LCA showed three survivor classes: (1) mild-to-moderate levels of all symptoms except for normal pain intensity; (2) mild anxiety, moderate fatigue, and normal levels of all other symptoms; and (3) normal levels of all symptoms. Lower mindfulness, acceptance, and values progress and higher cognitive fusion, psychological inflexibility, and values obstruction were associated with a greater likelihood of being in class 1 or 2 than in class 3.

conclusionFindings are consistent with the ACT model. Survivors with greater symptom burden reported greater withdrawal from personally meaningful activities and less acceptance of their cancer diagnosis and internal experiences (e.g., thoughts, feelings, symptoms). Findings provide strong justification for further testing of ACT to reduce symptom-related suffering in cancer survivors.

Indexed as

Acceptance and Commitment TherapyAdultAgedAged, 80 and overCancer SurvivorsFemaleHumansMaleMiddle AgedQuality of LifeAcceptance and commitment therapyCancer survivorsLatent class analysisMindfulnessPsychological flexibilitySymptoms

Identifiers

PMID33140248
PMCPMC8088450
OpenAlexW3095511790

What OpenQuestion holds

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LicenceTDM
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.