Evidence map›Paper›PMID 33140153›Full record

ArticleSurgical endoscopy2021

Laparoscopic versus open right posterior sectionectomy: an international, multicenter, propensity score-matched evaluation.

Nicky van der Heijde, Francesca Ratti, Luca Aldrighetti, Andrea Benedetti Cacciaguerra, Mehmet F Can, Mathieu D'Hondt, Fabrizio Di Benedetto, Arpad Ivanecz, Paolo Magistri, Krishna Menon and 4 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 6 countries.

Nicky van der HeijdeDepartment of Surgery, Southampton University Hospital, Southampton, UK.ORCID 0000-0003-0961-4108
Francesca RattiDepartment of Surgery, San Raffaele Hospital, Milan, Italy.
Luca AldrighettiDepartment of Surgery, San Raffaele Hospital, Milan, Italy.
Andrea Benedetti CacciaguerraHPB Surgery and Transplantation Unit, Department of Clinical and Experimental Medicine, Polytechnic University of Marche, Ancona, Italy.
Mehmet F CanDepartment of Surgery, Lokman Hekim University School of Medicine, Ankara, Turkey.
Mathieu D'HondtDepartment of Surgery, AZ Groeninge Hospital, Kortrijk, Belgium.
Fabrizio Di BenedettoDepartment of Surgery, University of Modena, Modena, Italy.
Arpad IvaneczDepartment of Abdominal and General Surgery, University Medical Centre Maribor, Maribor, Slovenia.
Paolo MagistriDepartment of Surgery, University of Modena, Modena, Italy.
Krishna MenonDepartment of Surgery, King's College Hospital, London, UK.
Michail PapoulasDepartment of Surgery, King's College Hospital, London, UK.
Marco VivarelliHPB Surgery and Transplantation Unit, Department of Clinical and Experimental Medicine, Polytechnic University of Marche, Ancona, Italy.
Marc G Besselink *Department of Surgery, Cancer Centre Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
Mohammed Abu Hilal *Department of Surgery, Southampton University Hospital, Southampton, UK. Abuhilal9@gmail.com.
King's College Hospital · GBMarche Polytechnic University · ITUniversity of Modena and Reggio Emilia · ITAmsterdam University Medical Centers · NLAZ Groeninge · BELokman Hekim Üniversitesi · TRSouthampton General Hospital · GBUniversity Clinical Centre Maribor · SIUniversity Hospital Southampton NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough laparoscopic liver resection has become the standard for minor resections, evidence is lacking for more complex resections such as the right posterior sectionectomy (RPS). We aimed to compare surgical outcomes between laparoscopic (LRPS) and open right posterior sectionectomy (ORPS).

methodsAn international multicenter retrospective study comparing patients undergoing LRPS or ORPS (January 2007-December 2018) was performed. Patients were matched based on propensity scores in a 1:1 ratio. Primary endpoint was major complication rate defined as Accordion ≥ 3 grade. Secondary endpoints included blood loss, length of hospital stay (LOS) and resection status. A sensitivity analysis was done excluding the first 10 LRPS patients of each center to correct for the learning curve. Additionally, possible risk factors were explored for operative time, blood loss and LOS.

resultsOverall, 399 patients were included from 9 centers from 6 European countries of which 150 LRPS could be matched to 150 ORPS. LRPS was associated with a shorter operative time [235 (195-285) vs. 247 min (195-315) p = 0.004], less blood loss [260 (188-400) vs. 400 mL (280-550) p = 0.009] and a shorter LOS [5 (4-7) vs. 8 days (6-10), p = 0.002]. Major complication rate [n = 8 (5.3%) vs. n = 9 (6.0%) p = 1.00] and R0 resection rate [144 (96.0%) vs. 141 (94.0%), p = 0.607] did not differ between LRPS and ORPS, respectively. The sensitivity analysis showed similar findings in the previous mentioned outcomes. In multivariable regression analysis blood loss was significantly associated with the open approach, higher ASA classification and malignancy as diagnosis. For LOS this was the open approach and a malignancy.

conclusionThis international multicenter propensity score-matched study showed an advantage in favor of LRPS in selected patients as compared to ORPS in terms of operative time, blood loss and LOS without differences in major complications and R0 resection rate.

Indexed as

LaparoscopyLiver NeoplasmsHepatectomyHumansLength of StayOperative TimePostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment OutcomeLaparoscopic surgeryLiver surgeryMinimally invasive surgeryOperative outcomesPropensity score matchingSurgical procedure

Identifiers

PMID33140153
PMCPMC8523385
OpenAlexW3095242506

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.