Evidence map›Paper›PMID 33139951›Full record

ArticleNature2020

Values encoded in orbitofrontal cortex are causally related to economic choices.

Sébastien Ballesta, Weikang Shi, Katherine E Conen, Camillo Padoa-Schioppa

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 145 citations in OpenAlex.

  1. Article
  2. Population geometries in frontal cortex coordinate value-based decisions.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
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  6. Article
  7. Article
  8. A hemispheric decoding principle for vestibular heading perception in the posterior sylvian area.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Optogenetic Hedonic Hotspots in the Orbitofrontal Cortex and Insula: Causing Enhancement of Sweetness "Liking".The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  10. Neuronal Activity in Orbitofrontal Cortex during Trinary Choices under Risk.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Memory erasure by dopamine-gated retrospective learning.bioRxiv : the preprint server for biology · 2026
    Article
  16. Article
  17. Article
  18. Article
  19. Ventral striatal astrocytes contribute to reinforcement learning.bioRxiv : the preprint server for biology · 2025
    Article
  20. Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Sébastien Ballesta *Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA.
Weikang Shi *Department of Neuroscience, Washington University in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0002-4068-1168
Katherine E ConenDepartment of Neuroscience, Washington University in St Louis, St Louis, MO, USA.ORCID http://orcid.org/0000-0003-3879-1680
Camillo Padoa-SchioppaDepartment of Neuroscience, Washington University in St Louis, St Louis, MO, USA. camillo@wustl.edu.ORCID http://orcid.org/0000-0002-7519-8790
Washington University in St. Louis · US

Funding

THE ROLE OF PREFRONTAL REGIONS IN ECONOMIC CHOICE AND CHOICE-GUIDED BEHAVIORR01DA032758 · NIDA · WASHINGTON UNIVERSITY · PI Camillo Padoa-Schioppa · 2012 to 2026
$5.4M
NEURONAL MECHANISMS OF GOOD-BASED ECONOMIC DECISIONSR01MH104494 · NIMH · WASHINGTON UNIVERSITY · PI PADOA-SCHIOPPA, CAMILLO · 2015 to 2025
$4.2M
Analyzing contextual adaptation in value-encoding neurons during economic choice.F31MH107111 · NIMH · WASHINGTON UNIVERSITY · PI CONEN, KATHERINE E · 2015 to 2016
$60k
NIDA NIH HHS R01 DA032758NIMH NIH HHS F31 MH107111NIMH NIH HHS R01 MH104494
6 · The paper itself

Abstract

In the eighteenth century, Daniel Bernoulli, Adam Smith and Jeremy Bentham proposed that economic choices rely on the computation and comparison of subjective values

Indexed as

Biobehavioral SciencesEconomicsModels, NeurologicalAnimalsDecision MakingElectric ConductivityElectric StimulationElectrodesMacaca mulattaMaleNeuronsPrefrontal Cortex

Identifiers

PMID33139951
PMCPMC7746614
OpenAlexW3097490630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.