Evidence map›Paper›PMID 33139942›Full record

ArticleNature neuroscience2020

Mesophasic organization of GABA

Yun-Tao Liu, Chang-Lu Tao, Xiaokang Zhang, Wenjun Xia, Dong-Qing Shi, Lei Qi, Cheng Xu, Rong Sun, Xiao-Wei Li, Pak-Ming Lau and 2 more

Open access · greenAbstract read
In one paragraph

Article in Nature neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
8.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 118 citations in OpenAlex.

  1. Article
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  6. Owl-vision-inspired near sensor computing.Nature communications · 2026
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  16. Molecular contacts in self-assembling clusters of membrane proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Resolving native GABANature · 2025
    Article
  19. Article
  20. Nanoscale architecture of synaptic vesicles and scaffolding complexes revealed by cryo-electron tomography.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Yun-Tao Liu *Center for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.ORCID http://orcid.org/0000-0003-2577-1859
Chang-Lu Tao *Center for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.ORCID http://orcid.org/0000-0003-0236-7239
Xiaokang Zhang *Interdisciplinary Center for Brain Information, The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, China.ORCID http://orcid.org/0000-0001-5073-2582
Wenjun XiaSchool of Mathematical Sciences, Jiangsu University, Zhenjiang, China.
Dong-Qing ShiCAS Key Laboratory of Brain Function and Disease, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Lei QiCAS Key Laboratory of Brain Function and Disease, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.
Cheng XuCenter for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.
Rong SunCenter for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.
Xiao-Wei LiCenter for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.
Pak-Ming LauCAS Key Laboratory of Brain Function and Disease, School of Life Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China. plau@ustc.edu.cn.ORCID http://orcid.org/0000-0001-9026-5501
Z Hong ZhouCalifornia NanoSystems Institute, University of California, Los Angeles, Los Angeles, CA, USA. hong.zhou@ucla.edu.ORCID http://orcid.org/0000-0002-8373-4717
Guo-Qiang BiCenter for Integrative Imaging, Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China. gqbi@ustc.edu.cn.ORCID http://orcid.org/0000-0001-8735-3818
University of Science and Technology of China · CNCalifornia NanoSystems Institute · USHKUST Shenzhen Research Institute · CNJiangsu University · CN

Funding

High-Resolution CryoEM Reconstruction of Large ComplexesR01GM071940 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHOU, Z HONG · 2006 to 2025
$5.0M
HIGH-END CRYOEM INSTRUMENT FOR UCLA ELECTRON IMAGING CTR FOR NANOMACHINES: AIDSS10RR023057 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2006 to 2006
$1.6M
Direct Detection Device for atomic resolution cryoEM of macromolecular complexesS10OD018111 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, Z HONG · 2014 to 2014
$598k
NCRR NIH HHS S10 RR023057NIGMS NIH HHS R01 GM071940NIH HHS S10 OD018111
6 · The paper itself

Abstract

Information processing in the brain depends on specialized organization of neurotransmitter receptors and scaffolding proteins within the postsynaptic density. However, how these molecules are organized in situ remains largely unknown. In this study, template-free classification of oversampled sub-tomograms was used to analyze cryo-electron tomograms of hippocampal synapses. We identified type-A GABA receptors (GABA

Indexed as

AnimalsComputer SimulationCryoelectron MicroscopyEntropyExcitatory Postsynaptic PotentialsFemaleHippocampusMembrane ProteinsNerve NetNeural InhibitionNeuronal PlasticityNeurotransmitter AgentsPatch-Clamp TechniquesPregnancyRatsRats, Sprague-DawleygephyrinMembrane ProteinsNeurotransmitter AgentsReceptors, GABA-A

Identifiers

PMID33139942
PMCPMC8048127
OpenAlexW3095611507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.