Evidence map›Paper›PMID 33139884›Full record

ArticleNature microbiology2021

β-Barrels covalently link peptidoglycan and the outer membrane in the α-proteobacterium Brucella abortus.

Pierre Godessart, Adélie Lannoy, Marc Dieu, Sander E Van der Verren, Patrice Soumillion, Jean-François Collet, Han Remaut, Patricia Renard, Xavier De Bolle

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 53 citations in OpenAlex.

  1. Outer Membrane-Peptidoglycan Anchoring inJournal of the American Chemical Society · 2026
    Article
  2. Article
  3. Activity Profiling of Mycobacterial L,D-Transpeptidases.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Peptidoglycan LD-Transpeptidases.Antibiotics (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Role of Outer Membrane Protein 16 inVeterinary sciences · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. TheAnnual review of microbiology · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Pierre GodessartResearch Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium.ORCID http://orcid.org/0000-0002-3465-960X
Adélie LannoyResearch Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium.
Marc DieuMaSUN, Mass Spectrometry Facility, University of Namur, Namur, Belgium.
Sander E Van der VerrenStructural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.ORCID http://orcid.org/0000-0002-8783-1194
Patrice SoumillionLIBST, UCLouvain, Louvain-la-Neuve, Belgium.ORCID http://orcid.org/0000-0003-4166-7867
Jean-François Colletde Duve Institute, Université Catholique de Louvain, Brussels, Belgium.
Han RemautStructural & Molecular Microbiology, VIB-VUB Centre for Structural Biology, Brussels, Belgium.ORCID http://orcid.org/0000-0002-9775-4102
Patricia RenardMaSUN, Mass Spectrometry Facility, University of Namur, Namur, Belgium.
Xavier De BolleResearch Unit in Microorganisms Biology (URBM), Department of Biology, Namur Research Institute for Life Sciences (NARILIS), Namur, Belgium. xavier.debolle@unamur.be.ORCID http://orcid.org/0000-0002-3845-3043
University of Namur · BEVrije Universiteit Brussel · BEde Duve Institute · BEUCLouvain · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gram-negative bacteria are surrounded by a cell envelope that comprises an outer membrane (OM) and an inner membrane that, together, delimit the periplasmic space, which contains the peptidoglycan (PG) sacculus. Covalent anchoring of the OM to the PG is crucial for envelope integrity in Escherichia coli. When the OM is not attached to the PG, the OM forms blebs and detaches from the cell. The Braun lipoprotein Lpp

Indexed as

Agrobacterium tumefaciensBacterial Outer Membrane ProteinsBrucella abortusCell MembraneCell WallLipoproteinsPeptidoglycanPeptidyl TransferasesProtein BindingBacterial Outer Membrane ProteinsLipoproteinsPeptidoglycanPeptidyl Transferases

Identifiers

PMID33139884
OpenAlexW3097046206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.