ArticleNature microbiology2021
β-Barrel proteins tether the outer membrane in many Gram-negative bacteria.
Open access · greenAbstract read
In one paragraph
Article in Nature microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 70 citations in OpenAlex.
- Peptide Mimetic Platform for Activity Profiling of Mycobacterial l,d-Transpeptidases.Biochemistry · 2026Article
- UV-C LED wavelength effects on inactivation kinetics, DNA damage and membrane integrity in drinking water indicator bacteria.Scientific reports · 2026Article
- Repeat Prolonged Chlorination at Low Dose Induces Chlorine Tolerance inEnvironment & health (Washington, D.C.) · 2026Article
- Activity Profiling of Mycobacterial L,D-Transpeptidases.bioRxiv : the preprint server for biology · 2026Article
- Insights into the complex formation of a trimeric autotransporter adhesin with a peptidoglycan-binding periplasmic protein.Cell surface (Amsterdam, Netherlands) · 2025Article
- Peptidoglycan LD-Transpeptidases.Antibiotics (Basel, Switzerland) · 2025Review
- Article
- An inner membrane protein is covalently attached to peptidoglycan in the γ-proteobacterium Dickeya dadantii.Communications biology · 2025Article
- Activation of the ChvG-ChvI pathway promotes survival during cell wall stress inMolecular biology of the cell · 2025Article
- PorV factor of the type IX secretion system and PosF porin act as adhesins in Riemerella anatipestifer infection.Veterinary research · 2025Article
- A software tool and strategy for peptidoglycomics, the high-resolution analysis of bacterial peptidoglycans via LC-MS/MS.Communications chemistry · 2025Article
- Primary role of the Tol-Pal complex in bacterial outer membrane lipid homeostasis.Nature communications · 2025Article
- LD-transpeptidase-mediated cell envelope remodeling enables developmental transitions and survival inJournal of bacteriology · 2025Article
- Exploring the mechanism of action of Jinqiancao granules against liver cirrhosis based on the liver-gut axis.Frontiers in pharmacology · 2025Article
- The Tol Pal system integrates maintenance of the three layered cell envelope.npj antimicrobials and resistance · 2024Review
- Immune Responses Elicited by Outer Membrane Vesicles of Gram-Negative Bacteria: Important Players in Vaccine Development.Life (Basel, Switzerland) · 2024Review
- Unveiling the impact ofInfection and immunity · 2024Article
- LD-transpeptidation is crucial for fitness and polar growth in Agrobacterium tumefaciens.PLoS genetics · 2024Article
- Control of bacterial cell wall autolysins by peptidoglycan crosslinking mode.Nature communications · 2024Article
- Seeing is believing: Illuminating the Gram-negative outer membrane with molecular dynamics simulations.Current opinion in structural biology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Kelsi M SandozRocky Mountain Laboratories, Laboratory of Bacteriology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. kms476@cornell.edu.ORCID http://orcid.org/0000-0002-6960-0560
Roger A Moore *Rocky Mountain Laboratories, Laboratory of Persistent Viral Disease, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Paul A Beare *Rocky Mountain Laboratories, Laboratory of Bacteriology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Ankur V Patel *Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0001-8161-3455
Robert E Smith *Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK.
Marshall BernProtein Metrics Inc., Cupertino, CA, USA.ORCID http://orcid.org/0000-0003-0342-9390
Hyea HwangSchool of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Connor J CooperBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0000-0002-5527-9948
Suzette A PriolaRocky Mountain Laboratories, Laboratory of Persistent Viral Disease, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Jerry M ParksBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0000-0002-3103-9333
James C GumbartSchool of Physics, Georgia Institute of Technology, Atlanta, GA, USA.
Stéphane MesnageDepartment of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, UK. s.mesnage@sheffield.ac.uk.ORCID http://orcid.org/0000-0003-1648-4890
Robert A HeinzenRocky Mountain Laboratories, Laboratory of Bacteriology, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, MT, USA. rheinzen@niaid.nih.gov.ORCID http://orcid.org/0000-0001-6870-4619
National Institutes of Health · USUniversity of Sheffield · GBGeorgia Institute of Technology · USOak Ridge National Laboratory · US
Funding
Cellular and Developmental Biology of Coxiella burnetiiZIAAI000931 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI HEINZEN, ROBERT A · 2009 to 2023
$11.8MMolecular Mechanisms of Prion Protein Amyloid FormationZIAAI001105 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI PRIOLA, SUZETTE ALISE · 2009 to 2025
$7.3MDynamic characterization of outer-membrane-protein biogenesis by the BAM and TAM complexesR01GM123169 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GUMBART, JAMES C. · 2017 to 2021
$1.4MBiotechnology and Biological Sciences Research Council BB/M011151/1Biotechnology and Biological Sciences Research Council BB/N00951/1Intramural NIH HHS ZIA AI000931Medical Research Council MR/S009272/1NIGMS NIH HHS R01 GM123169
Abstract
Gram-negative bacteria have a cell envelope that comprises an outer membrane (OM), a peptidoglycan (PG) layer and an inner membrane (IM)
Indexed as
Agrobacterium tumefaciensBacterial Outer Membrane ProteinsCell CycleCell MembraneCell WallCoxiella burnetiiEscherichia coliLegionella pneumophilaLipoproteinsMolecular Dynamics SimulationPeptidoglycanPeptidyl TransferasesProtein BindingBacterial Outer Membrane ProteinsLipoproteinsPeptidoglycanPeptidyl Transferases
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.