Evidence map›Paper›PMID 33139823›Full record

ArticleScientific reports2020

Harnessing the wisdom of crowds can improve guideline compliance of antibiotic prescribers and support antimicrobial stewardship.

Eva M Krockow, R H J M Kurvers, S M Herzog, J E Kämmer, R A Hamilton, N Thilly, G Macheda, C Pulcini

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Fluorescent optotracers for bacterial and biofilm detection and diagnostics.Science and technology of advanced materials · 2023
    Review
  6. The motor Wisdom of the Crowd.Journal of the Royal Society, Interface · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eva M KrockowDepartment of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, LE1 7RH, UK. emk12@le.ac.uk.
R H J M KurversCenter for Adaptive Rationality, Max-Planck Institute for Human Development, Berlin, Germany.
S M HerzogCenter for Adaptive Rationality, Max-Planck Institute for Human Development, Berlin, Germany.
J E KämmerCenter for Adaptive Rationality, Max-Planck Institute for Human Development, Berlin, Germany.
R A HamiltonSchool of Pharmacy, De Montfort University, Leicester, UK.
N ThillyUniversité de Lorraine, APEMAC, Nancy, France.
G MachedaUniversité de Lorraine, APEMAC, Nancy, France.
C PulciniUniversité de Lorraine, APEMAC, Nancy, France.

Funding

Wellcome Trust 204801/Z/16/Z
6 · The paper itself

Abstract

Antibiotic overprescribing is a global challenge contributing to rising levels of antibiotic resistance and mortality. We test a novel approach to antibiotic stewardship. Capitalising on the concept of "wisdom of crowds", which states that a group's collective judgement often outperforms the average individual, we test whether pooling treatment durations recommended by different prescribers can improve antibiotic prescribing. Using international survey data from 787 expert antibiotic prescribers, we run computer simulations to test the performance of the wisdom of crowds by comparing three data aggregation rules across different clinical cases and group sizes. We also identify patterns of prescribing bias in recommendations about antibiotic treatment durations to quantify current levels of overprescribing. Our results suggest that pooling the treatment recommendations (using the median) could improve guideline compliance in groups of three or more prescribers. Implications for antibiotic stewardship and the general improvement of medical decision making are discussed. Clinical applicability is likely to be greatest in the context of hospital ward rounds and larger, multidisciplinary team meetings, where complex patient cases are discussed and existing guidelines provide limited guidance.

Indexed as

Antimicrobial StewardshipComputer SimulationDecision MakingHumansInappropriate PrescribingInterdisciplinary CommunicationPatient Care TeamPractice Guidelines as Topic

Identifiers

PMID33139823
PMCPMC7608639

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.