Evidence map›Paper›PMID 33139786›Full record

ArticleScientific reports2020

Income is associated with hippocampal/amygdala and education with cingulate cortex grey matter volume.

M Lotze, M Domin, C O Schmidt, N Hosten, H J Grabe, N Neumann

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

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  14. Functional MRI in Radiology-A Personal Review.Healthcare (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M LotzeFunctional Imaging Unit, Center for Diagnostic Radiology and Neuroradiology, Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Walther-Rathenau-Str.46, 17475, Greifswald, Germany. martin.lotze@uni-greifswald.de.
M DominFunctional Imaging Unit, Center for Diagnostic Radiology and Neuroradiology, Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Walther-Rathenau-Str.46, 17475, Greifswald, Germany.
C O SchmidtInstitute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
N HostenDepartment of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
H J GrabeDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.
N NeumannFunctional Imaging Unit, Center for Diagnostic Radiology and Neuroradiology, Department of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Walther-Rathenau-Str.46, 17475, Greifswald, Germany.
Universitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Income and education are both elements of a person's socioeconomic status, which is predictive of a broad range of life outcomes. The brain's gray matter volume (GMV) is influenced by socioeconomic status and mediators related to an unhealthy life style. We here investigated two independent general population samples comprising 2838 participants (all investigated with the same MRI-scanner) with regard to the association of indicators of the socioeconomic status and gray matter volume. Voxel-based morphometry without prior hypotheses revealed that years of education were positively associated with GMV in the anterior cingulate cortex and net-equivalent income with gray matter volume in the hippocampus/amygdala region. Analyses of possible mediators (alcohol, cigarettes, body mass index (BMI), stress) revealed that the relationship between income and GMV in the hippocampus/amygdala region was partly mediated by self-reported stressors, and the association of years of education with GMV in the anterior cingulate cortex by BMI. These results corrected for whole brain effects (and therefore not restricted to certain brain areas) do now offer possibilities for more detailed hypotheses-driven approaches.

Indexed as

Educational StatusIncomeOrgan SizeAdultAgedAlcohol DrinkingAmygdalaBody Mass IndexFemaleGray MatterGyrus CinguliHealthy LifestyleHippocampusHumansMagnetic Resonance ImagingMale

Identifiers

PMID33139786
PMCPMC7608615
OpenAlexW3094954371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.