Evidence map›Paper›PMID 33139757›Full record

Trial reportScientific reports2020

Probiotic supplementation in marathonists and its impact on lymphocyte population and function after a marathon: a randomized placebo-controlled double-blind study.

Helena Batatinha, Edgar Tavares-Silva, Geovana S F Leite, Ayane S Resende, José A T Albuquerque, Christina Arslanian, Ricardo A Fock, Antônio H Lancha, Fabio S Lira, Karsten Krüger and 2 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 7 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 7 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  3. Effects of Probiotics Supplementation on Risk and Severity of Infections in Athletes: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
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  7. Impact of Probiotics on the Performance of Endurance Athletes: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
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  9. Eight Weeks ofNutrients · 2023
    Trial
  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Helena BatatinhaImmunometabolism Research Group, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil. batatinha.helena@usp.br.
Edgar Tavares-SilvaPrograma de pós-graduação em psicobiologia, Universidade Federal de São Paulo, Santos, Brazil.
Geovana S F LeiteLaboratory of Applied Nutrition and Metabolism, School of Physical Education and Sports, University of São Paulo, São Paulo, Brazil.
Ayane S ResendeLaboratory of Applied Nutrition and Metabolism, School of Physical Education and Sports, University of São Paulo, São Paulo, Brazil.
José A T AlbuquerqueDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Christina ArslanianDepartment of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Ricardo A FockDepartment of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil.
Antônio H LanchaLaboratory of Applied Nutrition and Metabolism, School of Physical Education and Sports, University of São Paulo, São Paulo, Brazil.
Fabio S LiraExercise and Immunometabolism Research Group, Post-Graduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), School of Technology and Sciences, Presidente Prudente, Brazil.
Karsten KrügerDepartment of Exercise Physiology and Sports Therapy, Justus-Liebig-University Giessen, Giessen, Germany.
Ronaldo Thomatieli-SantosPrograma de pós-graduação em psicobiologia, Universidade Federal de São Paulo, Santos, Brazil.
José C Rosa-NetoImmunometabolism Research Group, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BRUniversity of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotic supplementation arises as playing an immune-stimulatory role. High-intensity and -volume exercise can inhibit immune cell function, which threatens athletic performance and recovery. We hypothesized that 30 days of probiotic supplementation could stabilize the immune system of athletes preventing immune suppression after a marathon race. Twenty-seven male marathonists were double-blinded randomly into probiotic (Bifidobacterium-animalis-subsp.-Lactis (10 × 10

Indexed as

Dietary SupplementsLymphocyte CountAdultAthletic PerformanceBifidobacterium animalisCD8-Positive T-LymphocytesCytokinesDouble-Blind MethodHumansImmunomodulationInflammation MediatorsLactobacillus acidophilusMaleMarathon RunningProbioticsYoung AdultCytokinesInflammation Mediators

Identifiers

PMID33139757
PMCPMC7608678
OpenAlexW3095691412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.