Evidence map›Paper›PMID 33139656›Full record

ArticleNutrients2020

Gut Biofactory-Neurocompetent Metabolites within the Gastrointestinal Tract. A Scoping Review.

Karolina Skonieczna-Żydecka, Karolina Jakubczyk, Dominika Maciejewska-Markiewicz, Katarzyna Janda, Karolina Kaźmierczak-Siedlecka, Mariusz Kaczmarczyk, Igor Łoniewski, Wojciech Marlicz

Registry-linked trialOpen access · goldAbstract readScoping Review
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05567653 (Effects of 3-month Probiotic Mix Supplementation), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05567653 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of 3-month Probiotic Mix Supplementation (L. Helveticus R-0052, B. Longum R-0175) on Gut Microbiota and Metabolome, Endocannabinoid and Immune Systems Activation, Along With Symptoms of Fatigue in Professional Dancers

TypeinterventionalSponsorPoznan University of Physical EducationRan2022 to 2023Enrolled26ConditionsFatigue, Stress, JobArmsLactobacillus helveticus Rosell-52 and Bifidobacterium longum Rosell-175 (Sanprobi Stress), Starch (placebo)
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Probiotics: Symbiotic Relationship with the Animal Host.Animals : an open access journal from MDPI · 2022
    Review
  17. Review
  18. Microbiome Metabolites and Thyroid Dysfunction.Journal of clinical medicine · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karolina Skonieczna-ŻydeckaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Karolina JakubczykDepartment of Surgical Oncology, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdańsk, Poland.
Dominika Maciejewska-MarkiewiczDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Katarzyna JandaDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Karolina Kaźmierczak-SiedleckaDepartment of Surgical Oncology, Medical University of Gdansk, Smoluchowskiego 17, 80-214 Gdańsk, Poland.
Mariusz KaczmarczykDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.
Igor ŁoniewskiDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Wojciech MarliczDepartment of Gastroenterology, Pomeranian Medical University, 71-252 Szczecin, Poland.
Pomeranian Medical University · PLGdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota have gained much scientific attention recently. Apart from unravelling the taxonomic data, we should understand how the altered microbiota structure corresponds to functions of this complex ecosystem. The metabolites of intestinal microorganisms, especially bacteria, exert pleiotropic effects on the human organism and contribute to the host systemic balance. These molecules play key roles in regulating immune and metabolic processes. A subset of them affect the gut brain axis signaling and balance the mental wellbeing. Neurotransmitters, short chain fatty acids, tryptophan catabolites, bile acids and phosphatidylcholine, choline, serotonin, and

Indexed as

BacteriaBrainDysbiosisGastrointestinal MicrobiomeGastrointestinal TractHumansNeurotransmitter AgentsNeurotransmitter Agentsbrainmicrobiomeneurotransmittersshort chain fatty acidstryptophan

Identifiers

PMID33139656
PMCPMC7693392
OpenAlexW3094640747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.