Evidence map›Paper›PMID 33139421›Full record

ArticleJournal of clinical microbiology2021

Evaluation of a SARS-CoV-2 Surrogate Virus Neutralization Test for Detection of Antibody in Human, Canine, Cat, and Hamster Sera.

Ranawaka A P M Perera, Ronald Ko, Owen T Y Tsang, David S C Hui, Mike Y M Kwan, Christopher J Brackman, Esther M W To, Hui-Ling Yen, Kathy Leung, Samuel M S Cheng and 9 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Impact of SARS-CoV-2 variant mutations on susceptibility to monoclonal antibodies and antiviral drugs: a non-systematic review, April 2022 to October 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Ranawaka A P M PereraSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Ronald KoSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Owen T Y TsangInfectious Diseases Centre, Princess Margaret Hospital, Hospital Authority of Hong Kong, Kwai Chung, Hong Kong Special Administrative Region, China.
David S C HuiDepartment of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
Mike Y M KwanDepartment of Paediatric and Adolescent Medicine, Princess Margaret Hospital, Hospital Authority of Hong Kong, Kwai Chung, Hong Kong Special Administrative Region, China.
Christopher J BrackmanAgriculture, Fisheries and Conservation Department, Government of the Hong Kong Special Administrative Region, Hong Kong Special Administrative Region, China.
Esther M W ToAgriculture, Fisheries and Conservation Department, Government of the Hong Kong Special Administrative Region, Hong Kong Special Administrative Region, China.
Hui-Ling YenSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.ORCID 0000-0003-2493-3609
Kathy LeungSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Samuel M S ChengSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Kin Ho ChanSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Karl C K ChanSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Ka-Chi LiSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Linda SaifFood Animal Health Research Program, OARDC/The Ohio State University, Wooster, Ohio, USA.ORCID 0000-0002-3224-9009
Vanessa R BarrsJockey Club College of Veterinary Medicine & Life Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong Special Administrative Region, China.
Joseph T WuSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Thomas H C SitAgriculture, Fisheries and Conservation Department, Government of the Hong Kong Special Administrative Region, Hong Kong Special Administrative Region, China.
Leo L M PoonSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China.
Malik PeirisSchool of Public Health, The University of Hong Kong, Pok Fu Lam, Hong Kong Special Administrative Region, China malik@hku.hk.ORCID 0000-0001-8217-5995

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surrogate neutralization assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can be done without biosafety level 3 containment and in multiple species are desirable. We evaluate a recently developed surrogate virus neutralization test (sVNT) in comparison to 90% plaque reduction neutralization tests (PRNT

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCatsCOVID-19COVID-19 Serological TestingCricetinaeCross ReactionsDogsFemaleHumansImmune SeraMaleNeutralization TestsSARS-CoV-2Sensitivity and SpecificityAntibodies, NeutralizingAntibodies, ViralImmune SeraanimalantibodycaninecatCOVID-19hamsterhumanneutralizationSARS coronavirus 2SARS-CoV-2seroepidemiologyserologysurrogate virus neutralization

Identifiers

PMID33139421
PMCPMC8111130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.