Evidence map›Paper›PMID 33138948›Full record

ArticleSpatial and spatio-temporal epidemiology2020

Using residential histories in case-control analysis of lung cancer and mountaintop removal coal mining in Central Appalachia.

W J Christian, C J Walker, B Huang, J E Levy, E Durbin, S Arnold

Open access · greenAbstract read
In one paragraph

Article in Spatial and spatio-temporal epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Accuracy of LexisNexis-derived retrospective address histories in the Sister Study cohort.Journal of exposure science & environmental epidemiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

W J ChristianDept. of Epidemiology College of Public Health, University of Kentucky, Lexington, Kentucky, USA. Electronic address: jay.christian@uky.edu.
C J WalkerDept. of Epidemiology College of Public Health, University of Kentucky, Lexington, Kentucky, USA.
B HuangKentucky Cancer Registry, Lexington, Kentucky, USA.
J E LevyDept. of Geography College of Arts & Sciences, University of Kentucky, Lexington, Kentucky, USA.
E DurbinKentucky Cancer Registry, Lexington, Kentucky, USA.
S ArnoldMarkey Cancer Center, University of Kentucky, Lexington, Kentucky, USA.
University of Kentucky · USMarkey Cancer Center · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI KATHLEEN L. O'CONNOR · 2013 to 2026
$38.3M
Pilot Project ProgramP30ES026529 · NIEHS · UNIVERSITY OF KENTUCKY · PI John Anthony Bauer · 2017 to 2026
$15.4M
NCI NIH HHS P30 CA177558NIEHS NIH HHS P30 ES026529
6 · The paper itself

Abstract

Population-based ecological and cross-sectional studies have observed high risk for several cancers in areas of Central Appalachia where mountaintop removal coal mines operate. Case-control studies could provide stronger evidence of such relationships, but misclassification of exposure is likely when based on current residence, since individuals could have inhabited several residences with varying environmental exposures over many years. To address this, we used residential histories for individuals enrolled in a previous case-control study of lung cancer to assess residential proximity to mountaintop removal coal mining over a 30-year period, using both survey data and proprietary data from LexisNexis, Inc. Supplementing the survey data with LexisNexis data improved precision and completeness of geographic coordinates. Final logistic regression models revealed higher odds of high exposure among cases. These findings suggest that living in close proximity to mountaintop removal coal mining sites could increase risk for lung cancer, after adjusting for other relevant factors.

Indexed as

Coal MiningAdultAgedAge FactorsAppalachian RegionCase-Control StudiesConfounding Factors, EpidemiologicEnvironmental ExposureFemaleHumansLung NeoplasmsMaleMiddle AgedResidence CharacteristicsSex FactorsSpatio-Temporal AnalysisAppalachiaEnvironmentExposure assessmentLexisNexisLung cancerResidential history

Identifiers

PMID33138948
PMCPMC7609974
OpenAlexW3044614426

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.