Evidence map›Paper›PMID 33138929›Full record

SynthesisJournal of substance abuse treatment2020

A systematic review of patients' and providers' perspectives of medications for treatment of opioid use disorder.

Katharine Cioe, Breanne E Biondi, Rebecca Easly, Amanda Simard, Xiao Zheng, Sandra A Springer

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Journal of substance abuse treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
88citing papers in PubMed, 2 pooled it
12.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

88 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.

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28 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katharine CioeFrank H. Netter MD School of Medicine, 370 Bassett Road, North Haven, CT 06473, United States of America.
Breanne E BiondiYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, United States of America.
Rebecca EaslyFrank H. Netter MD School of Medicine, 370 Bassett Road, North Haven, CT 06473, United States of America.
Amanda SimardFrank H. Netter MD School of Medicine, 370 Bassett Road, North Haven, CT 06473, United States of America.
Xiao ZhengYale University, New Haven, CT 06520, United States of America.
Sandra A SpringerYale School of Medicine, Department of Internal Medicine, Section of Infectious Diseases, AIDS Program, United States of America; Center for Interdisciplinary Research on AIDS, Yale University School of Public Health, New Haven, CT, United States of America. Electronic address: Sandra.springer@yale.edu.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Medication Assisted Therapy as a Conduit to Care for HIV+ CJS Populations TransitK02DA032322 · NIDA · YALE UNIVERSITY · PI SPRINGER, SANDRA ANN · 2011 to 2022
$1.3M
NCATS NIH HHS UL1 TR001863NIDA NIH HHS K02 DA032322
6 · The paper itself

Abstract

backgroundThe opioid epidemic is a public health crisis. Medications for opioid use disorder (MOUD) include: 1) buprenorphine, 2) methadone, and 3) extended-release naltrexone (XR-NTX). Research should investigate patients' and providers' perspectives of MOUD since they can influence prescription, retention, and recovery.

methodsThis systematic review focused on patients' and providers' perceptions of MOUD. The review eligibility criteria included inclusion of the outcome of interest, in English, and involving persons ≥18 years. A PubMed database search yielded 1692 results; we included 152 articles in the final review.

resultsThere were 63 articles about buprenorphine, 115 articles about methadone, and 16 about naltrexone. Misinformation and stigma associated with MOUD were common patient themes. Providers reported lack of training and resources as barriers to MOUD.

conclusionThis review suggests that patients have significant misinformation regarding MOUD. Due to the severity of the opioid epidemic, research must consider the effects of patients' and providers' perspectives on treatment for OUD, including the effects on the type of MOUD prescribed, patient retention and adherence, and ultimately the number of patients treated for OUD, which will aid in curbing the opioid epidemic.

Indexed as

BuprenorphineOpioid-Related DisordersHumansMethadoneNaltrexoneOpiate Substitution TreatmentBuprenorphineMethadoneNaltrexoneBuprenorphine/naloxoneMethadoneMOUD, buprenorphineOpioid use disorderXR-naltrexone

Identifiers

PMID33138929
PMCPMC7609980
OpenAlexW3088021670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.