ArticleeLife2020
Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 79 citations in OpenAlex.
- Distinct cortical spatial representations learned along disparate visual pathways.Science advances · 2026Article
- Ecological Visual Processing in the Mouse.Annual review of neuroscience · 2026Review
- Predictive pursuit emerges in high-dimensional recurrent neural networks.bioRxiv : the preprint server for biology · 2026Article
- Egocentric Dominance in Spatial Representations: The Role of Environmental Familiarity in Building Cognitive Maps.Brain and behavior · 2026Article
- Anterior and posterior retrosplenial cortex form distinct visuospatial circuits in the mouse.Nature communications · 2026Article
- Article
- Thinking of Oneself as Someone: The Structure of Self-Representation.Cognitive science · 2026Article
- Differential modulation of aversive signaling by expectation across the cingulate cortex.bioRxiv : the preprint server for biology · 2026Article
- Continuous updating via self-motion compensates for weak allocentric spatial memory in aging.Psychology and aging · 2025Article
- A Hippocampal-Parietal Network for Reference Frame Coordination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex.Nature communications · 2025Article
- Building egocentric models of local space from retinal input.Current biology : CB · 2024Review
- Distinct codes for environment structure and symmetry in postrhinal and retrosplenial cortices.Nature communications · 2024Article
- Egocentric neural representation of geometric vertex in the retrosplenial cortex.Nature communications · 2024Article
- Retrosplenial inputs drive visual representations in the medial entorhinal cortex.Cell reports · 2024Article
- Hippocampal astrocytes induce sex-dimorphic effects on memory.Cell reports · 2024Article
- Border cells without theta rhythmicity in the medial prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Differentiated somatic gene expression is triggered in the dorsal hippocampus and the anterior retrosplenial cortex by hippocampal synaptic plasticity prompted by spatial content learning.Brain structure & function · 2024Article
- Navigation and the efficiency of spatial coding: insights from closed-loop simulations.Brain structure & function · 2024Article
- Coordinated head direction representations in mouse anterodorsal thalamic nucleus and retrosplenial cortex.eLife · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Spatial navigation requires landmark coding from two perspectives, relying on viewpoint-invariant and self-referenced representations. The brain encodes information within each reference frame but their interactions and functional dependency remains unclear. Here we investigate the relationship between neurons in the rat's retrosplenial cortex (RSC) and entorhinal cortex (MEC) that increase firing near boundaries of space. Border cells in RSC specifically encode walls, but not objects, and are sensitive to the animal's direction to nearby borders. These egocentric representations are generated independent of visual or whisker sensation but are affected by inputs from MEC that contains allocentric spatial cells. Pharmaco- and optogenetic inhibition of MEC led to a disruption of border coding in RSC, but not vice versa, indicating allocentric-to-egocentric transformation. Finally, RSC border cells fire prospective to the animal's next motion, unlike those in MEC, revealing the MEC-RSC pathway as an extended border coding circuit that implements coordinate transformation to guide navigation behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.